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Revue française d'allergologie et d'immunologie clinique, v.38 no.7 suppl.1, 1998년, pp.S222 - S226
Jaffuel, D. (Correspondence: Pr. Ph Godard, Service des Maladies Respiratoires, INSERM U454, CHU Arnaud de Villeneuve, 371 Av. du Doyen G. Giraud, 34295 MONTPELLIER Cedex 5, (France)) , Godard, Ph.
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SummaryDuring the past few years, significant advances in our understanding of the mechanisms by which cytokines act to induce inflammation has led to a number of novel approaches such as cytokine therapy, in the management of allergic diseases. Cytokine therapy includes cytokine antagonists (antibo...
RésuméCes dernières années ont vu des progrès significatifs dans notre compréhension des mécanismes par lesquels les cytokines agissent pour provoquer l'inflammation, ce qui a conduit à l'apparition d'un certain nombre d'approches originales comme le traitement par cytokines dans la prise en charge des maladies allergiques. Le traitement par cytokines comprend des antagonistes, des cytokines (anticorps aux cytokines et récepteurs solubles des cytokines), des antagonistes des récepteurs des cytokines et la restauration de l'équilibre entre Th-1 et Th-2. Les études sur l'animal, et in vitro, de la thérapie par cytokines semblent très prometteuses. Il reste à voir toutefois si la thérapie par cytokines va avoir une utilité pour le patient atopique et si elle sera aussi efficace que les thérapies conventionnelles avec moins d'effets latéraux.
J. Immunol. Mosmann 136 2348 1986 10.4049/jimmunol.136.7.2348 Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
FASEB J. Street 5 171 1991 10.1096/fasebj.5.2.1825981 Functional diversity of T-lymphocytes due to secretion of different cytokine patterns
Ann. Allergy Asthma. Immunol. Jirapongsananuruk 79 5 1997 10.1016/S1081-1206(10)63078-5 Clinical applications of cytokines: new directions in the therapy of atopic diseases
Am. J. Respir. Crit. Care Med. Naseer 155 845 1997 10.1164/ajrccm.155.3.9117015 Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy
J. Clin. Invest. Hamid 94 870 1994 10.1172/JCI117408 Differential cytokine gene expression in acute vs chronic atopic dermatitis
N. Engl. J. Med. Robinson 326 298 1992 10.1056/NEJM199201303260504 Predominant Th2-like bronchoalveolar T lymphocyte population in atopic asthma
Am. Rev. Respir. Dis. Walker 146 109 1992 10.1164/ajrccm/146.1.109 Allergic and non allergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
Thorax Djukanovic 51 575 1996 10.1136/thx.51.6.575 Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms
J. Immunol. Schleimer 148 1086 1992 10.4049/jimmunol.148.4.1086 Interleukin-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium: association with expression of VCAM-1
Immunol. Today Romagnogni 11 316 1990 10.1016/S0167-5699(10)80004-0 Regulation and deregulation of human IgE synthesis
J. Exp. Med. Lopez 167 642 1988 10.1084/jem.167.1.219 Recombinant human interleukin 5 is a selective activator of human eosinophil function
J. Immunol. Fujisawa 144 642 1990 10.4049/jimmunol.144.2.642 Regulatory effect of cytokines on eosinophil degranulating
Saito 85 2288 1988 Selective differentiation and proliferation of haematopoietic cells induced by recombinant interleukins
Eur. J. Immunol. Pene 18 929 1988 10.1002/eji.1830180615 Interleukin 5 enhances interleukin4-induced IgE production by normal human B Cells. The role of CD23 antigen
McKenzie 90 3735 1992 Interleukin-13, a novel cell-derived cytokine that regulates human monocyte and B cell function
Blood Trinchieri 84 4008 1994 10.1182/blood.V84.12.4008.bloodjournal84124008 Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T helper cell type 1 and cytotoxic lymphocytes
J. Immunol. Coffman 136 4538 1986 10.4049/jimmunol.136.12.4538 B Cell stimulatory factor-1 enhances the IgE response of LPS activated B cells
J. Allergy Clin. Immunol. Steinberg 96 209 1995 10.1016/S0091-6749(95)70010-2 Allergen-specific IgE production of commited B cells form allergic patients in vitro
J. Immunol. Finkelman 141 2335 1988 10.4049/jimmunol.141.7.2335 IL-4 is required to generate and sustain in vivo IgE responses
J. Immunol. Finkelman 149 3845 1992 10.4049/jimmunol.149.12.3845 Role of antigen-specific T cell help in the generation of in vivo antibody responses. II. Sustained antigen-specific T cell help is required to induce a specific antibody response
Am. Rev. Respir. Dis. Oosterhout 147 548 1993 10.1164/ajrccm/147.3.548 Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs
Eum 92 12290 1995 Eosinophil recruitment into the respiratory epithelium following antigenic challenge in hyper IgE mice is accompagnied by interleukin 5-dependent bronchial hyperresponsiveness
Int. Arch. allergy Immunol. Egan 107 321 1995 10.1159/000237014 Inhibition of pulmonary eosinophilia and hyperreactivity by antibodies to interleukin 5
Eur. J. Immunol. Lukacs 25 245 1995 10.1002/eji.1830250140 Macrophage inflammatory protein -1a influences eosinophil recruitment in antigen-specific airway inflammation
J. Immunol. Maliszewski 144 3028 1990 10.4049/jimmunol.144.8.3028 Cytokine receptors and B cell functions. I. Recombinant soluble receptors specially inhibit IL-1 and IL-4 induced B cell activities
Int. Arch. Allergy Immunol. Renz 109 167 1996 10.1159/000237216 Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor
Am. J. Respir. Cell Mol. Biol. Sim 11 473 1994 10.1165/ajrcmb.11.4.7917315 Interleukin-1 receptor antagonist protein inhibits the synthesis of IgE and proinflammatory cytokines by allergen-stimulated mononuclears cells
Am. J. Resp. Cell Mol. Biol. Watson 8 365 1993 10.1165/ajrcmb/8.4.365 Cytokines contribute to airway dysfunction in antigen-challenged guinea pigs: inhibition of airway hyperreactivity, pulmonary eosinophil accumulation and tumor necrosis generation by pretreatment with an interleukin-1 receptor antagonist
J. Allergy Clin. Immunol. Okada 95 1236 1995 10.1016/S0091-6749(95)70081-1 Potential role of interleukin-1 in allergen induced late asthmatic reactions in guinea pigs: suppressive effect of interleukin-1 receptor antagonist on late asthmatic reaction
J. Exp. Med. Aversa 178 2213 1993 10.1084/jem.178.6.2213 An IL-4 mutant protein inhibits both IL-4 and IL-13 induced human IgG4 and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13
J. Allergy Clin. Immunol. Boguniewicz 95 133 1995 10.1016/S0091-6749(95)70162-1 The effect of nebulized recombinant interferon-g in asthmatic airways
J. Allergy Clin. Immunol. Li 85 934 1990 10.1016/0091-6749(90)90080-N Lack of suppression of IgE production by recombinant interferon gamma: a controlled trial in patients with allergic rhinitis
Am. J. Med. Boguniewicz 88 365 1990 10.1016/0002-9343(90)90490-5 Recombinant gamma interferon in treatment of patients with atopic dermatitis and elevated IgE levels
Ann. Allergy Asthma. Immunol. Schneider 80 263 1998 10.1016/S1081-1206(10)62968-7 Long-term therapy with recombinant interferon gamma for atopic dermatitis
J. Immunol. Lack 152 2546 1994 10.4049/jimmunol.152.5.2546 Nebulized but not parenteral IFN-g decreases IgE production and normalizes airways function in a murine model of allergen sensitization
J. Clin. Invest Jaffe 88 297 1991 10.1172/JCI115291 Organ specific cytokine therapy, local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-g to the human lung
J. Clin. Invest. Kiniwa 90 262 1992 10.1172/JCI115846 Recombinant IL-12 suppresses the synthesis of IgE by interleukin-4 stimulated human lyphocytes
J. Exp. Med. Manetti 177 1199 1993 10.1084/jem.177.4.1199 Natural killer cell stimulatory factor (interleukin-12) induces T helper type 1 (Th1)-specific immune response and inhibits the development of IL-4 producing Th cells
J. Exp. Med. Gavett 182 1527 1995 10.1084/jem.182.5.1527 Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation and Th2 cytokine expression in mice
Am. J. Respir. Crit. Care Med. Kips 153 535 1996 10.1164/ajrccm.153.2.8564093 Interleukin-12 inhibits antigen induced airway hyperresponsiveness in mice
J. Immunol. Keane-Myers 160 1036 1998 10.4049/jimmunol.160.2.1036 Development of murine allergic asthma is dependent upon B7-2 costimulation
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