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Journal of neurochemistry, v.98 no.6, 2006년, pp.1697 - 1706
Butterfield, D. Allan (Department of Chemistry) , Abdul, Hafiz Mohmmad (Department of Chemistry) , Opii, Wycliffe (Department of Chemistry) , Newman, Shelley F. (Department of Chemistry) , Joshi, Gururaj (Department of Chemistry) , Ansari, Mubeen Ahmad (Department of Chemistry) , Sultana, Rukhsana (Department of Chemistry)
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AbstractProteolytic processing and phosphorylation of amyloid precursor protein (APP), and hyperphosphorylation of tau protein, have been shown to be increased in Alzheimer's disease (AD) brains, leading to increased production of &bgr;-amyloid (A&bgr;) peptides and neurofibrillary tangles, respecti...
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