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NTIS 바로가기Phytotherapy research : PTR, v.22 no.11, 2008년, pp.1552 - 1556
Lee, Sanghyun (Department of Applied Plant Science, Chung-Ang University, Anseong 456-756, Korea) , Park, Hee-Seung (Department of Applied Plant Science, Chung-Ang University, Anseong 456-756, Korea) , Notsu, Yohko (Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi 980-8578, Japan) , Ban, Hyun Seung (Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi 980-8578, Japan) , Kim, Yong Pil (Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi 980-8578, Japan) , Ishihara, Kenji (Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi 980-8578, Japan) , Hirasawa, Noriyasu (Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi 980-8578, Japan) , Jung, Sang Hoon (KIST Gangneung Institute, Gangneung 210-340, Korea) , Lee, Yeon Sil (Department of Food Science and Nutrition, Hallym University, Chuncheon 200-702, Korea) , Lim, Soon Sung (Department of Food Science and Nutrition, Hallym University, Chuncheon 200-702, Korea) , Park, Eun-Hee (College of Pharmacy, Sookmyung Women's University, Seoul 140-742, Korea) , Shin, Kuk Hyun (Natural Products Research Institute, Seoul National University, Seoul 110-460, Korea) , Seyama, Toshio (Fa) , Hong, JangJa , Ohuchi, Kazuo
The extract of the root of Acanthopanax chiisanensis Nakai is used for the treatment of inflammation. To analyse the action mechanism of this extract, the effect of hyperin (quercetin-3-O-&bgr;-d-galactose) isolated from the ethyl acetate fraction of the root of A. chiisanensis on nitrite production...
Ban, Hyun Seung, Lee, Sanghyun, Kim, Yong Pil, Yamaki, Kouya, Shin, Kuk Hyun, Ohuchi, Kazuo. Inhibition of prostaglandin E2 production by taiwanin C isolated from the root of Acanthopanax chiisanensis and the mechanism of action. Biochemical pharmacology, vol.64, no.9, 1345-1354.
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Hong, Jangja, Ishihara, Kenji, Zee, Okpyo, Ohuchi, Kazuo. Induction of apoptosis by apicularen A in human promyelocytic leukemia cell line HL-60.. Planta medica, vol.71, no.4, 306-312.
Hong, JangJa, Yamaki, Kouya, Ishihara, Kenji, Ahn, Jong Woong, Zee, OkPyo, Ohuchi, Kazuo. Induction of apoptosis of RAW 264.7 cells by the cytostatic macrolide apicularen A. Journal of pharmacy and pharmacology, vol.55, no.9, 1299-1306.
Hong, JangJa, Yokomakura, Aya, Nakano, Yasuhiro, Ban, Hyun Seung, Ishihara, Kenji, Ahn, Jong-Woong, Zee, OkPyo, Ohuchi, Kazuo. Induction of Nitric Oxide Production by the Cytostatic Macrolide Apicularen A [2,4-Heptadienamide,N-[(1E)-3-[(3S,5R,7R,9S)-3,4,5,6,7,8,9,10-octahydro-7,14 Dihydroxy-1-oxo-5,9-epoxy-1H-2-benzoxacyclododecin-3-yl]-1 propenyl]-, (2Z,4Z)-(9CI)] and Possible Role of Nitric Oxide in Apicularen A-Induced Apoptosis in RAW 264.7 Cells. The Journal of pharmacology and experimental therapeutics, vol.312, no.3, 968-977.
Hong, JangJa, Yokomakura, Aya, Nakano, Yasuhiro, Ishihara, Kenji, Kaneda, Makoto, Onodera, Mitsue, Nakahama, Ken-ichi, Morita, Ikuo, Niikura, Kazuaki, Ahn, Jong-Woong, Zee, OkPyo, Ohuchi, Kazuo. Inhibition of vacuolar-type (H+)-ATPase by the cytostatic macrolide apicularen A and its role in apicularen A-induced apoptosis in RAW 264.7 cells. FEBS letters, vol.580, no.11, 2723-2730.
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Kim, Yong Pil, Yamada, Masateru, Lim, Soon Sung, Lee, Sang Hyun, Ryu, Nama, Shin, Kuk Hyun, Ohuchi, Kazuo. Inhibition by tectorigenin and tectoridin of prostaglandin E2 production and cyclooxygenase-2 induction in rat peritoneal macrophages. Biochimica et biophysica acta, Molecular and cell biology of lipids, vol.1438, no.3, 399-407.
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Lahti, Aleksi, Jalonen, Ulla, Kankaanranta, Hannu, Moilanen, Eeva. c-Jun NH2-Terminal Kinase Inhibitor Anthra(1,9-cd)pyrazol-6(2H)-one Reduces Inducible Nitric-Oxide Synthase Expression by Destabilizing mRNA in Activated Macrophages. Molecular pharmacology, vol.64, no.2, 308-315.
Lee, M. K., Jeon, H. Y., Lee, K. Y., Kim, S. H., Ma, C. J., Sung, S. H., Lee, H.-S., Park, M. J., Kim, Y. C.. Inhibitory Constituents of Euscaphis japonica on Lipopolysaccharide-Induced Nitric Oxide Production in BV2 Microglia. Planta medica, vol.73, no.8, 782-786.
Lee, Sang-Hyun, Jung, Sang-Hoon, Lee, Yeon-Sil, Yamada, Masateru, Kim, Bak-Kwang, Ohuchi, Kazuo, Shin, Kuk-Hyun. Antiinflammatory Activity of Hyperin from Acanthopanax chiisanensis Roots. Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, vol.27, no.6, 628-632.
Min, Y.-D., Choi, C.-H., Bark, H., Son, H.-Y., Park, H.-H., Lee, S., Park, J.-W., Park, E.-K., Shin, H.-I., Kim, S.-H.. Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-κB and p38 MAPK in HMC-1 human mast cell line. Inflammation research : official journal of the European Histamine Research Society ... [et al.], vol.56, no.5, 210-215.
Ohuchi, Kazuo, Sugawara, Tadaki, Watanabe, Masako, Hirasawa, Noriyasu, Tsurufuji, Susumu, Fujiki, Hirota, Christensen, S. Brøgger, Sugimura, Takashi. Analysis of the stimulative effect of thapsigargin, a non‐TPA‐type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages. British journal of pharmacology : BJP, vol.94, no.3, 917-923.
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Shin, K H, Kim, Y P, Lim, S S, Lee, S, Ryu, N, Yamada, M, Ohuchi, K. Inhibition of prostaglandin E2 production by the isoflavones tectorigenin and tectoridin isolated from the rhizomes of Belamcanda chinensis.. Planta medica, vol.65, no.8, 776-777.
Yamaki, Kouya, Kim, Dong-Hyun, Ryu, Nama, Kim, Yong Pil, Shin, Kuk Hyun, Ohuchi, Kazuo. Effects of naturally occurring isoflavones on prostaglandin E2 production.. Planta medica, vol.68, no.2, 97-100.
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