최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기BMC cancer, v.8, 2008년, pp.286 - 286
Kang, Se Hun (Research Institute and Hospital, National Cancer Center, Republic of Korea) , Kang, Keon Wook (Department of Nuclear Medicine, School of Medicine, Seoul National University, Seoul, Korea) , Kim, Kyung-Hee (Research Institute and Hospital, National Cancer Center, Republic of Korea) , Kwon, Bumi (Research Institute and Hospital, National Cancer Center, Republic of Korea) , Kim, Seok-Ki (Research Institute and Hospital, National Cancer Center, Republic of Korea) , Lee, Ho-Young (Research Institute and Hospital, National Cancer Center, Republic of Korea) , Kong, Sun-Young (Research Institute and Hospital, National Cancer Center, Republic of Korea) , Lee, Eun Sook (Research Institute and Hospital, National Cancer Center, Republic of Korea) , Jang, Sang-Geun (Research Institute and Hospital, National Cancer Center, Republic of Korea) , Yoo, Byong Chul (Research Institute and Hospital, National Cancer Center, Republic of Korea)
BackgroundElucidating the molecular mechanisms by which tumors become resistant to Herceptin is critical for the treatment of Her2-overexpressed metastatic breast cancer.MethodsTo further understand Herceptin resistance mechanisms at the molecular level, we used comparative proteome approaches to an...
Slamon DJ Godolphin W Jones LA Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer Science 1989 244 707 712 2470152 10.1126/science.2470152
Hudziak RM Schlessinger J Ullrich A Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells Proc Natl Acad Sci USA 1987 84 7159 7163 2890160 10.1073/pnas.84.20.7159
Bouchard L Lamarre L Tremblay PJ Jolicoeur P Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene Cell 1989 57 931 936 2567634 10.1016/0092-8674(89)90331-0
Guy CT Webster MA Schaller M Parsons TJ Cardiff RD Muller WJ Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease Proc Natl Acad Sci USA 1992 89 10578 10582 1359541 10.1073/pnas.89.22.10578
Esteva FJ Valero V Booser D Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer J Clin Oncol 2002 20 1800 1808 11919237 10.1200/JCO.2002.07.058
Slamon DJ Leyland-Jones B Shak S Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2 N Engl J Med 2001 344 783 792 11248153 10.1056/NEJM200103153441101
Nahta R Esteva FJ Herceptin: mechanisms of action and resistance Cancer Lett 2006 232 123 138 16458110 10.1016/j.canlet.2005.01.041
Nahta R Yu D Hung MC Hortobagyi GN Esteva FJ Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer Nat Clin Pract Oncol 2006 3 269 280 16683005 10.1038/ncponc0509
Stephens P Hunter C Bignell G Lung cancer: intragenic ERBB2 kinase mutations in tumours Nature 2004 431 525 526 15457249 10.1038/431525b
Graus-Porta D Beerli RR Daly JM Hynes NE ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling EMBO J 1997 16 1647 1655 9130710 10.1093/emboj/16.7.1647
Spector NL Yarden Y Smith B Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells Proc Natl Acad Sci USA 2007 104 10607 10612 17556544 10.1073/pnas.0701286104
Shin YK Yoo BC Chang HJ Down-regulation of mitochondrial F1F0-ATP synthase in human colon cancer cells with induced 5-fluorouracil resistance Cancer Res 2005 65 3162 3170 15833846
Lehner I Niehof M Borlak J An optimized method for the isolation and identification of membrane proteins Electrophoresis 2003 24 1795 1808 12783457 10.1002/elps.200305387
Ciocca DR Calderwood SK Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications Cell Stress Chaperones 2005 10 86 103 16038406 10.1379/CSC-99r.1
Thanner F Sutterlin MW Kapp M Heat shock protein 27 is associated with decreased survival in node-negative breast cancer patients Anticancer Res 2005 25 1649 1653 16033076
Li DQ Wang L Fei F Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry Proteomics 2006 6 3352 3368 16637015 10.1002/pmic.200500617
Lemieux P Harvey J Guise T Low cell motility induced by hsp27 overexpression decreases osteolytic bone metastases of human breast cancer cells in vivo J Bone Miner Res 1999 14 1570 1575 10469286 10.1359/jbmr.1999.14.9.1570
Vargas-Roig LM Gago FE Tello O Aznar JC Ciocca DR Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy Int J Cancer 1998 79 468 475 9761114 10.1002/(SICI)1097-0215(19981023)79:5 3.0.CO;2-Z
Berrieman HK Cawkwell L O'Kane SL Smith L Lind MJ Hsp27 may allow prediction of the response to single-agent vinorelbine chemotherapy in non-small cell lung cancer Oncol Rep 2006 15 283 286 16328069
Kamada M So A Muramaki M Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells Mol Cancer Ther 2007 6 299 308 17218637 10.1158/1535-7163.MCT-06-0417
Hansen RK Parra I Lemieux P Oesterreich S Hilsenbeck SG Fuqua SA Hsp27 overexpression inhibits doxorubicin-induced apoptosis in human breast cancer cells Breast Cancer Res Treat 1999 56 187 196 10573111 10.1023/A:1006207009260
Ciocca DR Green S Elledge RM Heat shock proteins hsp27 and hsp70: lack of correlation with response to tamoxifen and clinical course of disease in estrogen receptor-positive metastatic breast cancer (a Southwest Oncology Group Study) Clin Cancer Res 1998 4 1263 1266 9607585
Zhang D Wong LL Koay ES Phosphorylation of Ser78 of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer Mol Cancer 2007 6 52 17697330 10.1186/1476-4598-6-52
Xu L Chen S Bergan RC MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer Oncogene 2006 25 2987 2998 16407830 10.1038/sj.onc.1209337
Rocchi P Beraldi E Ettinger S Increased Hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3-mediated suppression of apoptosis Cancer Res 2005 65 11083 11093 16322258 10.1158/0008-5472.CAN-05-1840
Casado P Zuazua-Villar P del Valle E Vincristine regulates the phosphorylation of the antiapoptotic protein HSP27 in breast cancer cells Cancer Lett 2007 247 273 282 16843591 10.1016/j.canlet.2006.05.005
Kindas-Mugge I Micksche M Trautinger F Modification of growth in small heat shock (hsp27) gene transfected breast carcinoma Anticancer Res 18 413 417 9568111
Lee JH Sun D Cho KJ Overexpression of human 27 kDa heat shock protein in laryngeal cancer cells confers chemoresistance associated with cell growth delay J Cancer Res Clin Oncol 2007 133 37 46 16906418 10.1007/s00432-006-0143-3
Kaaijk P Kaspers GJ Van Wering ER Cell proliferation is related to in vitro drug resistance in childhood acute leukaemia Br J Cancer 2003 88 775 781 12618889 10.1038/sj.bjc.6600787
Itamochi H Kigawa J Sugiyama T Kikuchi Y Suzuki M Terakawa N Low proliferation activity may be associated with chemoresistance in clear cell carcinoma of the ovary Obstet Gynecol 2002 100 281 287 12151151 10.1016/S0029-7844(02)02040-9
Maeda N Kawada N Seki S Stimulation of proliferation of rat hepatic stellate cells by galectin-1 and galectin-3 through different intracellular signaling pathways J Biol Chem 2003 278 18938 18944 12646584 10.1074/jbc.M209673200
Cuello M Ettenberg SA Clark AS Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2 Cancer Res 2001 61 4892 4900 11406568
Zhang D Tai LK Wong LL Chiu LL Sethi SK Koay ES Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer Mol Cell Proteomics 2005 4 1686 1696 16048908 10.1074/mcp.M400221-MCP200
Conroy SE Sasieni PD Amin V Wang DY Smith P Fentiman IS Latchman DS Antibodies to heat-shock protein 27 are associated with improved survival in patients with breast cancer Br J Cancer 1998 77 1875 1879 9667662
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
오픈액세스 학술지에 출판된 논문
※ AI-Helper는 부적절한 답변을 할 수 있습니다.