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Antinociceptive effect of paeoniflorin via spinal α2-adrenoceptor activation in diabetic mice

European journal of pain : EJP, v.15 no.10, 2011년, pp.1035 - 1039  

Lee, Keiko K. (Department of Hospital Administration, Center for Advanced Kampo Medicine and Clinical Research, Graduate School of Medicine, Juntendo University, Japan) ,  Omiya, Yuji (Tsumura Research Laboratories, Tsumura &) ,  Yuzurihara, Mitsutoshi (Co., Japan) ,  Kase, Yoshio (Tsumura Research Laboratories, Tsumura &) ,  Kobayashi, Hiroyuki (Co., Japan)

Abstract AI-Helper 아이콘AI-Helper

AbstractBackgroundShakuyakukanzoto (SKT) has been shown to modulate nociception in streptozotocin-induced diabetic mice via selective activation of the descending noradrenergic systems. However, the active components of SKT that exert the analgesic effect remain unknown. Here, we administered Glycyr...

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