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Serum fatty acid profiles using GC-MS and multivariate statistical analysis: potential biomarkers of Alzheimer's disease

Neurobiology of aging, v.33 no.6, 2012년, pp.1057 - 1066  

Wang, De-Cai (Corresponding author at: Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin, People's Republic of China. Tel.: +86-451-8750-2836) ,  Sun, Chang-Hao (fax: +86 451 8750 2836) ,  Liu, Li-Yan ,  Sun, Xiao-Hong ,  Jin, Xin-Wen ,  Song, Wen-Lei ,  Liu, Xiu-Qin ,  Wan, Xue-Lian

Abstract AI-Helper 아이콘AI-Helper

AbstractPrevious studies showed the relationship between fatty acids and the risk of developing Alzheimer's disease (AD). However, they did not address potential differences in free fatty acid (FFA) profiles that could be used to distinguish between AD patients and healthy controls. In the present s...

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참고문헌 (51)

  1. Pediatr. Res Anderson 27 89 1990 10.1203/00006450-199001000-00023 Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retian 

  2. Neurochem. Res Balazs 19 1131 1994 10.1007/BF00965146 Evidence of an oxidative challenge in the Alzheimer's brain 

  3. Neurology Barberger-Gateau 69 1921 2007 10.1212/01.wnl.0000278116.37320.52 Dietary patterns and risk of dementia: the Three-City cohort study 

  4. Brain Bogdanov 131 389 2008 10.1093/brain/awm304 Metabolomic profiling to develop blood biomarkers for Parkinson's disease 

  5. Neuroendocrinology Craft 70 146 1999 10.1159/000054469 Insulin metabolism in Alzheimer's disease differs according to apolipoprotein E genotype and gender 

  6. Lipids Conquer 35 1305 2000 10.1007/s11745-000-0646-3 Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment 

  7. J. Clin. Oncol Claudino 25 2840 2007 10.1200/JCO.2006.09.7550 Metabolomics: available results, current research projects in breast cancer and future applications 

  8. J. Alzheimers Dis de La Torre 4 497 2002 10.3233/JAD-2002-4606 Alzheimer's disease: how does it start? 

  9. Ann. N. Y. Acad. Sci de La Torre 977 196 2002 10.1111/j.1749-6632.2002.tb04817.x Vascular basis of Alzheimer's pathogenesis 

  10. Neurol. Res de La Torre 26 517 2004 10.1179/016164104225016254 Alzheimer's disease is a vasocognopathy: a new term to describe its nature 

  11. Eriksson 2001 Multi-and megavariate data analysis-Part. 1: Basic principles and applications 

  12. Comp. Funct. Genomics Fiehn 2 155 2001 10.1002/cfg.82 Combining genomics, metabolome analysis, and biochemical modeling to understand metabolic networks 

  13. FEBS Lett Goux 366 81 1995 10.1016/0014-5793(95)00486-S Analysis of the core components of Alzheimer paired helical filaments-A gas chromatography/mass spectrometry characterization of fatty acids, carbohydrates and long-chain bases 

  14. J. Neurosci Green 27 4385 2007 10.1523/JNEUROSCI.0055-07.2007 Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-{beta} and tau pathology via a mechanism involving presenilin 1 levels 

  15. Clin. Nutr Guérin 28 141 2009 10.1016/j.clnu.2009.01.014 Characteristics of Alzheimer's disease patients with a rapid weight loss during a six-year follow-up 

  16. Pharmacol. Res Horrocks 40 211 1999 10.1006/phrs.1999.0495 Health benefits of docosahexaenoic acid (DHA) 

  17. Arch. Neurol Hebert 8 1119 2003 10.1001/archneur.60.8.1119 Alzheimer disease in the US population: prevalence estimates using the 2000 census 

  18. J. Am. Vet. Med. Assoc Heinemann 228 700 2006 10.2460/javma.228.5.700 Docosahexaenoic acid and neurologic development in animals 

  19. J. Lipid Res Ikemoto 42 1655 2001 10.1016/S0022-2275(20)32220-3 Reversibility of n-3 fatty acid deficiency-induced alterations of learning behavior in the rat: level of n-6 fatty acids as another critical factor 

  20. J. Nutr Innis 137 855 2007 10.1093/jn/137.4.855 Dietary (n-3) Fatty Acids and Brain Development 

  21. Lipids Kyle 34 S245 1999 10.1007/BF02562306 Low serum docosahexaenoic acid is a significant risk factor for Alzheimer's dementia 

  22. Acta Neurol. Scand. Suppl Kivipelto 185 50 2006 10.1111/j.1600-0404.2006.00685.x Cholesterol as a risk factor for Alzheimer's disease-epidemiological evidence 

  23. J. Clin. Invest Lukiw 115 2774 2005 10.1172/JCI25420 A role for docosahexaenoic acid derived neuroprotectin D1 in neural cell survival and Alzheimer disease 

  24. J. Neurosci Lim 12 3032 2005 10.1523/JNEUROSCI.4225-04.2005 A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model 

  25. Neurology McKhann 34 939 1984 10.1212/WNL.34.7.939 Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease 

  26. Arch. Neurol Morris 60 940 2003 10.1001/archneur.60.7.940 Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease 

  27. Evid Rep Technol Assess (Summ) Maclean 1 2005 Effects of omega-3 fatty acids on cognitive function with aging, dementia, and neurological diseases 

  28. J. Chromatogr. B Anal. Technol. Biomed. Life Sci Mariani 827 65 2005 10.1016/j.jchromb.2005.04.023 Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview 

  29. Annu. Rev. Cell Dev. Biol Marszalek 21 633 2005 10.1146/annurev.cellbio.21.122303.120624 Docosahexanoic acid, fatty acid-interacting proteins and neuronal function: breastmilk and fish are good for you 

  30. Neurobiol. Aging Migliore 26 587 2005 10.1016/j.neurobiolaging.2004.10.002 Searching for the role and the most suitable biomarkers of oxidative stress in Alzheimer's disease and in other neurodegenerative diseases 

  31. Am. J. Clin. Nutr. Nurk 86 1470 2007 10.1093/ajcn/86.5.1470 Cognitive performance among the elderly and dietary fish intake: the Hordal and Health Study 

  32. Expert Rev. Neurother Nourhashémi 8 691 2008 10.1586/14737175.8.5.691 Weight loss as a predictor of dementia and Alzheimer's disease? 

  33. Neurobiol. Aging Pettegrew 15 117 1994 10.1016/0197-4580(94)90152-X Alterations of cerebral metabolism in probable Alzheimer's disease: a preliminary study 

  34. Arch. Neurol Praticò 59 972 2002 10.1001/archneur.59.6.972 Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease 

  35. Anal. Chim. Acta Paik 576 55 2006 10.1016/j.aca.2006.01.070 Urinary polyamines and N-acetylated polyamines in four patients with Alzheimer's disease as their N-ethoxycarbonyl-N-pentafluoropropionyl derivatives by gas chromatography-mass spectrometry in selected ion monitoring mode 

  36. Biochemistry Ramanadham 37 4553 1998 10.1021/bi9722507 Electrospray ionization mass spectrometric analyses of phospholipids from rat and human pancreatic islets and subcellular membranes: comparison to other tissues and implications for membrane fusion in insulin exocytosis 

  37. J. Biol. Chem Roberts 273 13605 1998 10.1074/jbc.273.22.13605 Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid 

  38. Biochim. Biophys. Acta Ramanadham 1484 251 2000 10.1016/S1388-1981(00)00022-6 Electrospray ionization mass spectrometric analyses of phospholipids from INS-1 insulinoma cells: comparison to pancreatic islets and effects of fatty acid supplementation on phospholipid composition and insulin secretion 

  39. Lipids Soderberg 26 421 1991 10.1007/BF02536067 Fatty acid composition of brain phospholipids in aging and in Alzheimer's disease 

  40. JAMA Small 16 1363 1997 10.1001/jama.1997.03550160083043 Diagnosis and treatment of Alzheimer disease and related disorders 

  41. Lancet Neurol Shobab 4 841 2005 10.1016/S1474-4422(05)70248-9 Cholesterol in Alzheimer's disease 

  42. Arch. Neurol Schaefer 63 1545 2006 10.1001/archneur.63.11.1545 Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study 

  43. Nutr. Rev Uauy 64 S24 2006 10.1301/nr.2006.may.S24-S33 Nutrition in brain development and aging: role of essential fatty acids 

  44. EMBO J Wold 44 4158 1998 10.1093/emboj/17.14.4158 Effects of purified SeqA protein on oriC-dependent DNA replication in vitro 

  45. Chin. J. Gen. Pract Wang 5 358 2006 The prevalence of Alzheimer's disease in China 

  46. Clin. Chem Wikoff 53 2169 2007 10.1373/clinchem.2007.089011 Metabolomics identifies perturbations in human disorders of propionate metabolism 

  47. Rapid Commun. Mass Spectrom Xue 22 3061 2008 10.1002/rcm.3708 A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry 

  48. J. Chromatogr. B Anal. Technol. Biomed. Life Sci Yang 813 53 2004 10.1016/j.jchromb.2004.09.023 Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles 

  49. FEBS Lett Yi 580 6837 2006 10.1016/j.febslet.2006.11.043 Plasma fatty acid metabolic profiling and biomarkers of type 2 diabetes mellitus based on GC/MS and PLS-LDA 

  50. Arch. Neurol Zhang 62 447 2005 10.1001/archneur.62.3.447 Dementia subtypes in China: prevalence in Beijing, Xi'an, Shanghai, and Chengdu 

  51. Am. J. Clin. Nutr Zeisel 86 542 2007 10.1093/ajcn/86.3.542 Nutrigenomics and metabolomics will change clinical nutrition and public health practice: insights from studies on dietary requirements for choline 

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