[논문]Effect of Lactobacillus plantarum CJLP243 on the growth performance and cytokine response of weaning pigs challenged with enterotoxigenic Escherichia coli1

Lee, J. S.; Awji, E. G.; Lee, S. J.; Tassew, D. D.; Park, Y. B.; Park, K. S.; Kim, M. K.; Kim, B.; Park, S. C.

doi:10.2527/jas.2011-4434

Effect of Lactobacillus plantarum CJLP243 on the growth performance and cytokine response of weaning pigs challenged with enterotoxigenic Escherichia coli1 원문보기

Journal of animal science, v.90 no.11, 2012년, pp.3709 - 3717

Lee, J. S. (Laboratory of Clinical Pharmacokinetics and Pharmacodynamics, College of Veterinary Medicine, Kyungpook National University, Daegu, 702-701, Republic of Korea) , Awji, E. G. (Laboratory of Clinical Pharmacokinetics and Pharmacodynamics, College of Veterinary Medicine, Kyungpook National University, Daegu, 702-701, Republic of Korea) , Lee, S. J. (Laboratory of Clinical Pharmacokinetics and Pharmacodynamics, College of Veterinary Medicine, Kyungpook National University, Daegu, 702-701, Republic of Korea) , Tassew, D. D. (Laboratory of Clinical Pharmacokinetics and Pharmacodynamics, College of Veterinary Medicine, Kyungpook National University, Daegu, 702-701, Republic of Korea) , Park, Y. B. (Department of Animal Science & Biotechnology, College of Agriculture and Life Science, Chungnam National University, Daejeon, 305-764, Republic of Korea) , Park, K. S. (Department of Animal Science & Biotechnology, College of Agriculture and Life Science, Chungnam National University, Daejeon, 305-764, Republic of Korea) , Kim, M. K. (Department of Animal Science & Biotechnology,) , Kim, B. , Park, S. C.

Abstract ▼ AI-Helper

The purpose of the present study was to evaluate the effect of diets containing Lactobacillus plantarum CJLP243 on the growth and cytokine response of weaning pigs (Sus scrofa) challenged with enterotoxigenic Escherichia coli (ETEC). In a 28-d experiment (14 d before and 14 d after challenge), a total of 108 pigs at 20 1 d of age were allotted to 1 of 6 diets. These were a control diet without ETEC challenge (CON) and 5 treatment diets with ETEC challenge, including a control diet with ETEC challenge (negative control, NC); a positive control diet containing antibiotics (PC); control diet plus (10(8), 10(9), or 10(10)) cfu/kg L. plantarum CJLP243 (T1, T2, and T3, respectively). After challenge, NC showed the least ADFI, whereas PC and T3 had the greatest ADFI (P = 0.002). The ADG of PC, T2, and T3 were greater (P = 0.001) than that of CON, NC, and T1 during wk 1 to wk 2. During wk 3 to wk 4, a marked decline was seen in NC (P = 0.001) compared with CON, whereas PC and T3 showed increased ADG (P = 0.001). The overall ADG of PC and T3 were greater (P < 0.001) than the remaining groups. The PC and T3 had the greatest G:F during the second 2 wk (P = 0.002), and the overall 4-wk experimental period (P = 0.003). At 3 h after challenge, all groups except CON had greater rectal temperatures (RT; P < 0.05). The RT decreased to prechallenge temperatures at 9 h (PC and T3), 24 h (T1 and T2), and remained increased until d 7 in NC. At 7 and 14 d postinfection, the number of animals detected positive for ETEC by PCR assay was the greatest in NC; however, the PC group had the fewest ETEC-positive animals (P < 0.05), which was similar to T3. All challenged pigs, except T2, had greater concentrations of serum haptoglobin compared with CON, with the greatest concentration observed in NC (P < 0.001). Challenged pigs had increased serum concentrations of tumor necrosis factor alpha (TNF-α) 3 to 48 h postinfection, with the greatest concentration of TNF-α at 48 h observed in NC (P < 0.05). Similarly, greater (P < 0.05) serum concentrations of interferon-γ were observed for 9 h (T1 and T3), 24 h (T2 and PC), and 48 h (NC) postinfection. The serum concentration of IL-6 increased (P < 0.05) for 3 h in T3 and 24 h in NC. In conclusion, our findings suggest that L. plantarum CJLP243, at a concentration of 10(10) cfu/kg, may serve as a potential alternative to antibiotic supplementation to improve the growth and health performance of weaning pigs, especially during acute inflammation of the gut after bacterial infections.

참고문헌 (29)

J. Anim. Sci. Balaji 78 1885 2000 10.2527/2000.7871885x Acute phase responses of pigs challenged orally with Salmonella typhimurium

상세보기
J. Anim. Sci. Bhandari 86 836 2008 10.2527/jas.2006-822 Evaluation of alternatives to antibiotics using an Escherichia coli K88+ model of piglet diarrhea: effects on gut microbial ecology

상세보기
Curr. Opin. Gastroenterol. Boirivant 23 679 2007 10.1097/MOG.0b013e3282f0cffc The mechanism of action of probiotics

상세보기
J. Anim. Sci. Bosi 82 1764 2004 10.2527/2004.8261764x Spray-dried plasma improves growth performance and reduces inflammatory status of weaned pigs challenged with enterotoxigenic Escherichia coli K88

상세보기
Antonie Van Leeuwenhoek. Chang 80 193 2001 10.1023/A:1012213728917 Selection of a potential probiotic Lactobacillus strain and subsequent in vivo studies

상세보기
Eur. J. Immunol. Chapat 34 2520 2004 10.1002/eji.200425139 Lactobacillus casei reduces CD8+ T cell-mediated skin inflammation

상세보기
Br. J. Nutr. De Vrese 88 Suppl 1 S59 2002 10.1079/BJN2002630 Probiotics and non-intestinal infectious conditions

상세보기
J. Am. Vet. Med. Assoc. Dritz 220 1690 2002 10.2460/javma.2002.220.1690 An Evaluation of in-feed antimicrobial regimens in multi-site pig production systems

상세보기
J. Anim. Sci. Gebru 88 3880 2010 10.2527/jas.2010-2939 Effect of probiotic-, bacteriophage-, or organic acid-supplemented feeds or fermented soybean meal on the growth performance, acute-phase response, and bacterial shedding of grower pigs challenged with Salmonella enterica serotype Typhimurium

상세보기
J. Anim. Sci. Huang 17 401 2004 Effects of Lactobacillus on the performance, diarrhea incidence, VFA concentration and gastrointestinal microbial flora of weaning pigs. Asian-Austr
J. Anim. Sci. Johnson 75 1244 1997 10.2527/1997.7551244x Inhibition of growth by proinflammatory cytokines: an integrated view

상세보기
FEMS Microbiol. Ecol. Konstantinov 66 599 2008 10.1111/j.1574-6941.2008.00517.x Feeding of Lactobacillus sobrius reduces Escherichia coli F4 levels in the gut and promotes growth of infected piglets

상세보기
Int. J. Food Microbiol. Lee 148 80 2011 10.1016/j.ijfoodmicro.2011.05.003 Evaluation of probiotic characteristics of newly isolated Lactobacillus spp. Immune modulation and longevity

상세보기
FEMS. Immunol. Med. Microbiol. Marquardt 23 283 1999 10.1111/j.1574-695X.1999.tb01249.x Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia coli K88+ infection in neonatal and early-weaned piglets

상세보기
Asian-Aust. J. Anim. Sci. Metzler 18 1353 2005 10.5713/ajas.2005.1353 Microflora management in the gastrointestinal tract of piglets

원문보기 상세보기
Anim. Feed Sci. Technol. Mikkelsen 117 107 2004 10.1016/j.anifeedsci.2004.07.015 Effect of fructo-oligosaccharides and transgalacto-oligosaccharide on microbial populations and microbial activity in the gastrointestinal tract of piglets

상세보기
Appl. Environ. Microbiol. Mikkelsen 70 3485 2004 10.1128/AEM.70.6.3485-3492.2004 Effects of physical properties of feed on microbial ecology and survival of Salmonella enterica serovar Typhimurium in the pig gastrointestinal tract

상세보기
Livestock Sci. Modesto 122 248 2009 10.1016/j.livsci.2008.08.017 A novel strategy to select Bifidobacterium strains and prebiotics as natural growth promoters in newly weaned pigs

상세보기
Health Res. Rev. Nava 6 105 2005 10.1079/AHR2005103 Probiotic alternatives to reduce gastrointestinal infections: The poultry experience. Anim

상세보기
Nutrient requirements of swine. NRC 10th ed. 1998
Eur. J. Clin. Nutr. Perdigon 56 Suppl 4 S21 2002 10.1038/sj.ejcn.1601658 Interaction of lactic acid bacteria with the gut immune system

상세보기
Anim. Biotechnol. Pettigrew 17 207 2006 10.1080/10495390600956946 Reduced use of antibiotic growth promoters in diets fed to weanling pigs: Dietary tools, Part 1

상세보기
Dig. Dis. Sci. Schroeder 51 724 2006 10.1007/s10620-006-3198-8 Preventive effects of the probiotic Escherichia coli strain Nissle 1917 on acute secretory diarrhea in a pig model of intestinal infection

상세보기
Anim. Biotechnol. Stein 17 217 2006 10.1080/10495390600957191 Reduced use of antibiotic growth promoters in diets fed to weanling pigs: Dietary tools, part 2

상세보기
J. Anim. Sci. Turner 80 1939 2002 10.2527/2002.8071939x Effects of a Quillaja saponaria extract on growth performance and immune function of weanling pigs challenged with Salmonella typhimurium

상세보기
J. Anim. Sci. Turner 80 1947 2002 10.2527/2002.8071947x Effects of Ascophyllum nodosum extract on growth performance and immune function of young pigs challenged with Salmonella

상세보기
J. Anim. Sci. Weber 86 871 2008 10.2527/jas.2007-0330 Effects of adding fibrous feedstuffs to the diet of young pigs on growth performance, intestinal cytokines, and circulating acute-phase proteins

상세보기
Animal. Wellock 2 834 2008 10.1017/S1751731108002048 Effects of dietary protein supply, weaning age and experimental enterotoxigenic Escherichia coli infection on newly weaned pigs

상세보기
PLoS One. Zanello 4 e18573 2011 10.1371/journal.pone.0018573 Saccharomyces cerevisiae modulates immune gene expressions and inhibits ETEC-mediated ERK1/2 and p38 signaling pathways in intestinal epithelial cells

상세보기

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Effect of Lactobacillus plantarum CJLP243 on the growth performance and cytokine response of weaning pigs challenged with enterotoxigenic Escherichia coli1 원문보기

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