다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
Life sciences, v.160, 2016년, pp.47 - 56
Chandrika, Bhavya Balan (Inter University Centre for Bioscience and Department of Biotechnology & Microbiology, Kannur University Thalassery Campus, Kannur 670 661, Kerala, India) , Steephan, Mathew (Govt Brennen College, Kannur University, Kannur 670 661, Kerala, India) , Kumar, T.R. Santhosh (Rajiv Gandhi Centre for Biotechnology, Trivandrum 695014, Kerala, India) , Sabu, A. (Inter University Centre for Bioscience and Department of Biotechnology & Microbiology, Kannur University Thalassery Campus, Kannur 670 661, Kerala, India) , Haridas, M. (Inter University Centre for Bioscience and Department of Biotechnology & Microbiology, Kannur University Thalassery Campus, Kannur 670 661, Kerala, India)
AI-Helper
Abstract Aim Aberrant human epidermal growth factor receptor-2 (HER2) expression and constitutive mutant activation of its tyrosine kinase domain account for tumor aggression and therapy resistance in many types of cancers with major share in breast cancer cases. HER2 specific treatment modalities ...
Cancer Cell Int. Abaza 15 46 2015 10.1186/s12935-015-0194-0 Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer
J. Biol. Chem. Aertgeerts 286 18756 2011 10.1074/jbc.M110.206193 Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 protein
Fundam. Clin. Pharmacol. Alshatwi 27 581 2013 10.1111/j.1472-8206.2012.01061.x The apoptotic effect of hesperetin on human cervical cancer cells is mediated through cell cycle arrest, death receptor, and mitochondrial pathways
Int. J. Clin. Pharm. Ayres 37 365 2015 10.1007/s11096-015-0070-y Trastuzumab induced cardiotoxicity in HER2 positive breast cancer patients attended in a tertiary hospital
PLoS One Bai 8 2013 10.1371/journal.pone.0079901 Comparison of HER2 and phospho-HER2 expression between biopsy and resected breast cancer specimens using a quantitative assessment method
J. Agric. Food Chem. Bak 59 10286 2011 10.1021/jf2017594 A synthetic naringenin derivative, 5-hydroxy-7,4′-diacetyloxyflavanone-N-phenyl hydrazone (N101-43), induces apoptosis through up-regulation of Fas/FasL expression and inhibition of PI3K/Akt signaling pathways in non-small-cell lung cancer cells
Clin. Cancer Res. Brabender 7 1850 2001 Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival
Clin. Exp. Metastasis Bracke 9 13 1991 10.1007/BF01831706 Effect of catechins and citrus flavonoids on invasion in vitro
Anal. Quant. Cytol. Histol. Brunner 32 78 2010 EGFR (HER) family protein expression and cytogenetics in 219 squamous cell carcinomas of the upper respiratory tract: ERBB2 overexpression independent prediction of poor prognosis
IUBMB Life Bulzomi 64 690 2012 10.1002/iub.1049 The naringenin-induced proapoptotic effect in breast cancer cell lines holds out against a high bisphenol a background
Growth Factors Burgess 26 263 2008 10.1080/08977190802312844 EGFR family: structure physiology signalling and therapeutic targets
Int. J. Cancer Caltagirone 87 595 2000 10.1002/1097-0215(20000815)87:4<595::AID-IJC21>3.0.CO;2-5 Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential
Br. J. Cancer Carlsson 90 2344 2004 10.1038/sj.bjc.6601881 HER2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review
Nat. Rev. Clin. Oncol. Castaneda 6 308 2009 10.1038/nrclinonc.2009.68 Targeted therapies: combined lapatinib and paclitaxel in HER2-positive breast cancer
Breast Care (Basel) Cetin 8 67 2013 10.1159/000346829 Lapatinib plus capecitabine for HER2-positive advanced-stage breast cancer in elderly women: review of the Anatolian Society of Medical Oncology (ASMO) experience
Pharmacogn. Rev. Chahar 5 1 2011 10.4103/0973-7847.79093 Flavonoids: a versatile source of anticancer drugs
Clin. Cancer Res. Chen 14 6730 2008 10.1158/1078-0432.CCR-08-0581 Acquired resistance to small molecule ErbB2 tyrosine kinase inhibitors
Acta Pharm. Sin. B Chen 1 197 2011 10.1016/j.apsb.2011.10.007 Mechanisms of acquired resistance to tyrosine kinase inhibitors
Nutr. Cancer Choi 59 115 2007 10.1080/01635580701419030 Hesperetin induced G1-phase cell cycle arrest in human breast cancer MCF-7 cells: involvement of CDK4 and p21
Biochem. Soc. Trans. Claus 42 831 2014 10.1042/BST20140043 A role for the pseudokinase HER3 in the acquired resistance against EGFR- and HER2-directed targeted therapy
Biochem. Soc. Trans. Creedon 42 822 2014 10.1042/BST20140109 Exploring mechanisms of acquired resistance to HER2 (human epidermal growth factor receptor 2)-targeted therapies in breast cancer
Hepato-Gastroenterology Dai 59 2439 2012 Trastuzumab combined with docetaxel-based regimens in previously treated metastatic gastric cancer patients with HER2 over-expression
Front. Oncol. den Hollander 3 250 2013 10.3389/fonc.2013.00250 Targeted therapy for breast cancer prevention
J. Natl. Cancer Inst. Ellis 106 2014 10.1093/jnci/dju212 HER2-positive breast cancer, intrinsic subtypes, and tailoring therapy
Curr. Opin. Genet. Dev. Engelman 18 73 2008 10.1016/j.gde.2008.01.004 Acquired resistance to tyrosine kinase inhibitors during cancer therapy
Oncologist Eroglu 19 135 2014 10.1634/theoncologist.2013-0283 Human epidermal growth factor receptor family-targeted therapies in the treatment of HER2-overexpressing breast cancer
Expert. Rev. Anticancer. Ther. Gajria 11 263 2011 10.1586/era.10.226 HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies
Exp. Cell Res. Hatkevich 327 331 2014 10.1016/j.yexcr.2014.05.017 A naringenin-tamoxifen combination impairs cell proliferation and survival of MCF-7 breast cancer cells
Food Sci. Hum. Wellness He 2 146 2013 10.1016/j.fshw.2013.08.002 Consumption of soybean, soy foods, soy isoflavones and breast cancer incidence: differences between Chinese women and women in western countries and possible mechanisms
Breast Cancer (Dove Med. Press) Hurvitz 4 35 2012 Role of lapatinib alone or in combination in the treatment of HER2-positive breast cancer
Drugs Today (Barc.) Johnston 42 441 2006 10.1358/dot.2006.42.7.985637 Lapatinib: a novel EGFR/HER2 tyrosine kinase inhibitor for cancer
Health Technol. Assess. Jones 13 Suppl. 3 1 2009 Lapatinib for the treatment of HER2-overexpressing breast cancer
J. Am. Chem. Soc. Jorgensen 118 11225 1996 10.1021/ja9621760 Development and testing of the OPLS all-atom force field on conformational energetics and properties of organic liquids
J. Phys. Chem. B Kaminski 105 6474 2001 10.1021/jp003919d Evaluation and reparametrization of the OPLS-AA force field for proteins via comparison with accurate quantum chemical calculations on peptides
In Vivo Kandaswami 19 895 2005 The antitumor activities of flavonoids
Med. Oncol. Kostyal 29 1486 2012 10.1007/s12032-011-0025-7 Trastuzumab and lapatinib modulation of HER2 tyrosine/threonine phosphorylation and cell signaling
Onco Targets Ther. Koutras 1 5 2008 10.2147/OTT.S3842 The epidermal growth factor receptor family in breast cancer
Ann. Oncol. Krop 26 113 2015 10.1093/annonc/mdu486 Trastuzumab emtansine (T-DM1) versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer and central nervous system metastases: a retrospective, exploratory analysis in EMILIA
Chem. Biol. Interact. Kumar 205 128 2013 10.1016/j.cbi.2013.06.020 The anticancer potential of flavonoids isolated from the stem bark of Erythrina suberosa through induction of apoptosis and inhibition of STAT signaling pathway in human leukemia HL-60 cells
Mol. Cell. Biochem. Lee 347 103 2011 10.1007/s11010-010-0618-z Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells
Mol. Carcinog. Li 52 134 2013 10.1002/mc.21839 Quercetin-3-methyl ether inhibits lapatinib-sensitive and -resistant breast cancer cell growth by inducing G(2)/M arrest and apoptosis
Mol. Med. Rep. Liao 10 1531 2014 10.3892/mmr.2014.2375 Naringenin inhibits migration of bladder cancer cells through downregulation of AKT and MMP2
PLoS One Lou 7 2012 10.1371/journal.pone.0050956 Naringenin decreases invasiveness and metastasis by inhibiting TGF-beta-induced epithelial to mesenchymal transition in pancreatic cancer cells
Anti-Cancer Drugs Modjtahedi 20 851 2009 10.1097/CAD.0b013e3283330590 Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities
Int. J. Oncol. Navolanic 22 237 2003 EGFR family signaling and its association with breast cancer development and resistance to chemotherapy (review)
Breast Nielsen 22 1 2013 10.1016/j.breast.2012.09.008 Efficacy of HER2-targeted therapy in metastatic breast cancer. Monoclonal antibodies and tyrosine kinase inhibitors
Food Chem. Toxicol. Park 46 3684 2008 10.1016/j.fct.2008.09.056 Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells
Anti Cancer Agents Med. Chem. Pratheeshkumar 12 1159 2012 10.2174/187152012803833035 Cancer prevention with promising natural products: mechanisms of action and molecular targets
Protein Cell Qin 2 507 2011 10.1007/s13238-011-1056-8 Naringenin reduces lung metastasis in a breast cancer resection model
Med. Res. Rev. Ren 23 519 2003 10.1002/med.10033 Flavonoids: promising anticancer agents
J. Nutr. Gerontol. Geriatr. Romagnolo 31 206 2012 10.1080/21551197.2012.702534 Flavonoids and cancer prevention: a review of the evidence
Clin. Exp. Metastasis Tatsuta 18 657 2000 10.1023/A:1013133803806 Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats
Adv. Exp. Med. Biol. Wahle 698 36 2010 10.1007/978-1-4419-7347-4_4 Plant phenolics in the prevention and treatment of cancer
Mini-Rev. Med. Chem. Wang 10 1058 2010 10.2174/1389557511009011058 Flavopiridol, the first cyclin-dependent kinase inhibitor: recent advances in combination chemotherapy
Curr. Drug Deliv. Wolfram 2015 Hesperetin liposomes for cancer therapy
Tumour Biol. Wu 2015 Hesperetin induces apoptosis of esophageal cancer cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species
Food Funct. Yang 2015 10.1039/C5FO00570A Evaluation of antioxidative and antitumor activities of extracted flavonoids from Pink Lady apples in human colon and breast cancer cell lines
Thyroid Yin 9 369 1999 10.1089/thy.1999.9.369 Growth inhibitory effects of flavonoids in human thyroid cancer cell lines
Dig. Dis. Sci. Zhang 60 2985 2015 10.1007/s10620-015-3696-7 Hesperetin induces the apoptosis of gastric cancer cells via activating mitochondrial pathway by increasing reactive oxygen species
Int. J. Oncol. Zhou 37 551 2010 Dietary polyphenol quercetin targets pancreatic cancer stem cells
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.