[논문]Stressful Events and Serum Concentration of Substance P in Acne Patients

Rokowska-Waluch, Anita; Pawlaczyk, Mariola; Cybulski, Marcin; Ż; urawski, Jakub; Kaczmarek, Mariusz; Michalak, Michał; Mojs, Ewa

doi:10.5021/ad.2016.28.4.464

[국내논문] Stressful Events and Serum Concentration of Substance P in Acne Patients 원문보기

Annals of dermatology, v.28 no.4, 2016년, pp.464 - 469

Rokowska-Waluch, Anita (Division of Skin Disease Prophylaxis, Department of Geriatric Medicine and Gerontology, Poznan University of Medical Sciences, Poznan, Poland.) , Pawlaczyk, Mariola (Division of Skin Disease Prophylaxis, Department of Geriatric Medicine and Gerontology, Poznan University of Medical Sciences, Poznan, Poland.) , Cybulski, Marcin (Department of Clinical Psychology, Poznan University of Medical Sciences, Poznan, Poland.) , Żurawski, Jakub (Department of Biology and Environmental Study, Poznan University of Medical Sciences, Poznan, Poland.) , Kaczmarek, Mariusz (Department of Clinical Immunology, Poznan University of Medical Sciences, Poznan, Poland.) , Michalak, Michał (Department of Computer Science and Statistics, Poznan University of Medical Sciences, Poznan, Poland.) , Mojs, Ewa (Department of Clinical Psychology, Poznan University of Medical Sciences, Poznan, Poland.)

Abstract ▼ AI-Helper

BackgroundPsychological stress is an important factor of acne pathogenesis. Stress related production of hormones, cytokines and neuropeptides may result in the chronic course and exacerbations of the disease.ObjectiveThe aim of the study was to evaluate the relationship between acne severity, intensity of emotional stress and serum concentration of substance P (scSP), to compare the intensity of adversities, psychological stress and scSP in acne patients with healthy controls and to compare coping techniques for stress.MethodsThe study consisted of 80 patients. Emotional stress was analyzed with the use of social readjustment rating scale, whereas the methods of coping with stress were assessed with the coping inventory for stressful situation questionnaire. The blood concentration of substance P was analyzed by enzyme-linked immunosorbent assay method in a group of 40 patients with acne vulgaris and in control subjects.ResultsThere was no statistically significant difference between the severity of acne and the intensity of stress. Acne patients presented a higher average scSP than the controls. No statistically significant correlation was observed between the severity of acne and scSP; however, the intensity of stress correlated with scSP in the control group. The evaluation of methods of coping with stress showed significantly higher rate for the avoidance-oriented coping among acne patients.ConclusionThe number of stressful events is not a factor that determines the severity of acne. The course of the disease may depend on tolerance to stress and methods of coping with stress.

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참고문헌 (18)

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[국내논문] Stressful Events and Serum Concentration of Substance P in Acne Patients 원문보기

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