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Scientific reports, v.7, 2017년, pp.10487 -
Wu, Jun (Salk Institute for Biological Studies, 10010 N. Torrey Pines Rd., La Jolla, CA 92037 USA) , Vilarino, Marcela (Department of Animal Science, University of California Davis, One Shields Avenue, Davis, CA 95616 USA) , Suzuki, Keiichiro (Salk Institute for Biological Studies, 10010 N. Torrey Pines Rd., La Jolla, CA 92037 USA) , Okamura, Daiji (Universidad Cató) , Bogliotti, Yanina Soledad (lica San Antonio de Murcia, Campus de los Jeró) , Park, Insung (nimos 135, Guadalupe, 30107 Spain) , Rowe, Joan (Department of Animal Science, University of California Davis, One Shields Avenue, Davis, CA 95616 USA) , McNabb, Bret (Department of Animal Science, University of California Davis, One Shields Avenue, Davis, CA 95616 USA) , Ross, Pablo Juan (School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, CA 95616 USA) , Belmonte, Juan Carlos Izpisua (School of Veterinary Medicine, University of California Davis, One Shields Avenue, Davis, CA 95616 USA)
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Genome editing using programmable nucleases has revolutionized biomedical research. CRISPR-Cas9 mediated zygote genome editing enables high efficient production of knockout animals suitable for studying development and relevant human diseases. Here we report efficient disabling pancreatogenesis in p...
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