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Cell reports, v.24 no.5, 2018년, pp.1363 - 1376
Nuciforo, Sandro (Department of Biomedicine, University Hospital Basel, University of Basel) , Fofana, Isabel (Department of Biomedicine, University Hospital Basel, University of Basel) , Matter, Matthias S. (Institute of Pathology, University Hospital Basel, University of Basel) , Blumer, Tanja (Department of Biomedicine, University Hospital Basel, University of Basel) , Calabrese, Diego (Department of Biomedicine, University Hospital Basel, University of Basel) , Boldanova, Tujana (Department of Biomedicine, University Hospital Basel, University of Basel) , Piscuoglio, Salvatore (Institute of Pathology, University Hospital Basel, University of Basel) , Wieland, Stefan (Department of Biomedicine, University Hospital Basel, University of Basel) , Ringnalda, Femke (Institute of Molecular Health Sciences, ETH Zurich) , Schwank, Gerald (Institute of Molecular Health Sciences, ETH Zurich Switze) , Terracciano, Luigi M. , Ng, Charlotte K.Y. , Heim, Markus H.
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Summary Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the second most frequent cause of cancer-related mortality worldwide. The multikinase inhibitor sorafenib is the only treatment option for advanced HCC. Due to tumor heterogeneity, its efficacy greatly varies between...
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