최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기PloS one, v.9 no.2, 2014년, pp.e88508 -
Nagpure, Bhushan Vijay (Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore) , Bian, Jin-Song (Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore)
Alzheimer's disease (AD) is the leading cause of senile dementia in today's society. Its debilitating symptoms are manifested by disturbances in many important brain functions, which are influenced by adenosine. Hence, adenosinergic system is considered as a potential therapeutic target in AD treatm...
1 Reitz C , Brayne C , Mayeux R ( 2011 ) Epidemiology of Alzheimer disease . Nat Rev Neurol 7 : 137 – 152 . 21304480
2 Castellani RJ , Rolston RK , Smith MA ( 2010 ) Alzheimer Disease . Disease-a-Month 56 : 484 – 546 . 20831921
3 Selkoe DJ ( 2002 ) Alzheimer's disease is a synaptic failure . Science 298 : 789 – 791 . 12399581
4 Mattson MP ( 2004 ) Pathways towards and away from Alzheimer's disease . Nature 430 : 631 – 639 . 15295589
5 Selkoe DJ ( 1991 ) The molecular pathology of Alzheimer's disease . Neuron 6 : 487 – 498 . 1673054
6 Cummings JL , Vinters HV , Cole GM , Khachaturian ZS ( 1998 ) Alzheimer's disease: etiologies, pathophysiology, cognitive reserve, and treatment opportunities . Neurology 51 : S2 – 17 discussion S65-17.
7 de Mendonça A , Ribeiro JA ( 2001 ) Adenosine and synaptic plasticity . Drug Development Research 52 : 283 – 290 .
8 Ribeiro JA , Sebastião AM , de Mendonça A ( 2002 ) Adenosine receptors in the nervous system: pathophysiological implications . Progress in Neurobiology 68 : 377 – 392 . 12576292
9 Fredholm BB, Chen J-F, Cunha RA, Svenningsson P, Vaugeois J-M (2005) Adenosine and Brain Function. International Review of Neurobiology: Academic Press. pp. 191–270.
10 Cunha RA ( 2001 ) Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors . Neurochemistry International 38 : 107 – 125 . 11137880
11 Abbracchio MP , Cattabeni F ( 1999 ) Brain adenosine receptors as targets for therapeutic intervention in neurodegenerative diseases . Ann N Y Acad Sci 890 : 79 – 92 . 10668415
12 Albasanz JL , Perez S , Barrachina M , Ferrer I , Martin M ( 2008 ) Up-regulation of adenosine receptors in the frontal cortex in Alzheimer's disease . Brain Pathol 18 : 211 – 219 . 18241242
13 Fuxe K , Marcellino D , Borroto-Escuela DO , Guescini M , Fernandez-Duenas V , et al ( 2010 ) Adenosine-dopamine interactions in the pathophysiology and treatment of CNS disorders . CNS Neurosci Ther 16 : e18 – 42 . 20345970
14 Blum D , Hourez R , Galas MC , Popoli P , Schiffmann SN ( 2003 ) Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics . Lancet Neurol 2 : 366 – 374 . 12849153
15 Boison D ( 2006 ) Adenosine kinase, epilepsy and stroke: mechanisms and therapies . Trends in Pharmacological Sciences 27 : 652 – 658 . 17056128
16 Markesbery WR ( 1997 ) Oxidative stress hypothesis in Alzheimer's disease . Free Radic Biol Med 23 : 134 – 147 . 9165306
17 Christen Y ( 2000 ) Oxidative stress and Alzheimer disease . Am J Clin Nutr 71 : 621S – 629S . 10681270
18 Park J, Gupta R (2013) Adenosine Metabolism, Adenosine Kinase, and Evolution. In: Masino S, Boison D, editors. Adenosine: Springer New York. pp. 23–54.
19 Headrick JP , Willis RJ ( 1990 ) Adenosine formation and energy metabolism: a 31P-NMR study in isolated rat heart . Am J Physiol 258 : H617 – 624 . 2316676
20 Ballard FJ ( 1970 ) Adenine nucleotides and the adenylate kinase equilibrium in livers of foetal and newborn rats . Biochem J 117 : 231 – 235 . 5420030
21 Decking UK , Schlieper G , Kroll K , Schrader J ( 1997 ) Hypoxia-induced inhibition of adenosine kinase potentiates cardiac adenosine release . Circ Res 81 : 154 – 164 . 9242176
22 Bhatia M , Wong FL , Fu D , Lau HY , Moochhala SM , et al ( 2005 ) Role of hydrogen sulfide in acute pancreatitis and associated lung injury . FASEB J 19 : 623 – 625 . 15671155
23 Jeong SO , Pae HO , Oh GS , Jeong GS , Lee BS , et al ( 2006 ) Hydrogen sulfide potentiates interleukin-1beta-induced nitric oxide production via enhancement of extracellular signal-regulated kinase activation in rat vascular smooth muscle cells . Biochem Biophys Res Commun 345 : 938 – 944 . 16707097
24 Lee SW , Hu YS , Hu LF , Lu Q , Dawe GS , et al ( 2006 ) Hydrogen sulphide regulates calcium homeostasis in microglial cells . Glia 54 : 116 – 124 . 16718684
25 Yong QC , Choo CH , Tan BH , Low CM , Bian JS ( 2010 ) Effect of hydrogen sulfide on intracellular calcium homeostasis in neuronal cells . Neurochem Int 56 : 508 – 515 . 20026367
26 Nagai Y , Tsugane M , Oka J , Kimura H ( 2004 ) Hydrogen sulfide induces calcium waves in astrocytes . FASEB J 18 : 557 – 559 . 14734631
27 Yamada K , Inagaki N ( 2005 ) Neuroprotection by KATP channels . Journal of Molecular and Cellular Cardiology 38 : 945 – 949 . 15910879
28 Tan BH , Wong PTH , Bian J-S ( 2010 ) Hydrogen sulfide: A novel signaling molecule in the central nervous system . Neurochemistry International 56 : 3 – 10 . 19703504
29 Hu LF , Lu M , Hon Wong PT , Bian JS ( 2011 ) Hydrogen sulfide: neurophysiology and neuropathology . Antioxid Redox Signal 15 : 405 – 419 . 20812864
30 Qu K , Lee SW , Bian JS , Low CM , Wong PT ( 2008 ) Hydrogen sulfide: neurochemistry and neurobiology . Neurochem Int 52 : 155 – 165 . 17629356
31 Abe K , Kimura H ( 1996 ) The possible role of hydrogen sulfide as an endogenous neuromodulator . J Neurosci 16 : 1066 – 1071 . 8558235
32 Li L , Rose P , Moore PK ( 2011 ) Hydrogen sulfide and cell signaling . Annu Rev Pharmacol Toxicol 51 : 169 – 187 . 21210746
33 Hu LF , Lu M , Tiong CX , Dawe GS , Hu G , et al ( 2010 ) Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models . Aging Cell 9 : 135 – 146 . 20041858
34 Hu L-F , Wong PTH , Moore PK , Bian J-S ( 2007 ) Hydrogen sulfide attenuates lipopolysaccharide-induced inflammation by inhibition of p38 mitogen-activated protein kinase in microglia . Journal of Neurochemistry 100 : 1121 – 1128 . 17212697
35 Lu M , Hu LF , Hu G , Bian JS ( 2008 ) Hydrogen sulfide protects astrocytes against H(2)O(2)-induced neural injury via enhancing glutamate uptake . Free Radic Biol Med 45 : 1705 – 1713 . 18848879
36 Reiffenstein RJ , Hulbert WC , Roth SH ( 1992 ) TOXICOLOGY OF HYDROGEN-SULFIDE . Annual Review of Pharmacology and Toxicology 32 : 109 – 134 .
37 Mackay K , Mochly-Rosen D ( 2001 ) Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through epsilon protein kinase C. Cardiovasc Res . 50 : 65 – 74 .
38 Pan TT , Neo KL , Hu LF , Yong QC , Bian JS ( 2008 ) H2S preconditioning-induced PKC activation regulates intracellular calcium handling in rat cardiomyocytes . Am J Physiol Cell Physiol 294 : C169 – 177 . 17989210
39 Yong QC , Pan T-T , Hu L-F , Bian J-S ( 2008 ) Negative regulation of β-adrenergic function by hydrogen sulphide in the rat hearts . Journal of Molecular and Cellular Cardiology 44 : 701 – 710 . 18329040
40 Farmery MR , Tjernberg LO , Pursglove SE , Bergman A , Winblad B , et al ( 2003 ) Partial purification and characterization of gamma-secretase from post-mortem human brain . J Biol Chem 278 : 24277 – 24284 . 12697771
41 Kolachala V , Asamoah V , Wang L , Srinivasan S , Merlin D , et al ( 2005 ) Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase . J Biol Chem 280 : 4048 – 4057 . 15550390
42 Satoh J , Kuroda Y ( 1999 ) Constitutive and cytokine-regulated expression of presenilin-1 and presenilin-2 genes in human neural cell lines . Neuropathol Appl Neurobiol 25 : 492 – 503 . 10632899
43 Canals M , Angulo E , Casado V , Canela EI , Mallol J , et al ( 2005 ) Molecular mechanisms involved in the adenosine A and A receptor-induced neuronal differentiation in neuroblastoma cells and striatal primary cultures . J Neurochem 92 : 337 – 348 . 15663481
44 Tomita S , Kirino Y , Suzuki T ( 1998 ) A Basic Amino Acid in the Cytoplasmic Domain of Alzheimer's β-Amyloid Precursor Protein (APP) Is Essential for Cleavage of APP at the α-Site . Journal of Biological Chemistry 273 : 19304 – 19310 . 9668120
45 Nordstedt C , Gandy SE , Alafuzoff I , Caporaso GL , Iverfeldt K , et al ( 1991 ) Alzheimer beta/A4 amyloid precursor protein in human brain: aging-associated increases in holoprotein and in a proteolytic fragment . Proc Natl Acad Sci U S A 88 : 8910 – 8914 . 1924350
46 Cunha RA ( 2005 ) Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade . Purinergic Signal 1 : 111 – 134 . 18404497
47 Arendash GW , Schleif W , Rezai-Zadeh K , Jackson EK , Zacharia LC , et al ( 2006 ) Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production . Neuroscience 142 : 941 – 952 . 16938404
48 Takahashi RN , Pamplona FA , Prediger RDS ( 2008 ) Adenosine receptor antagonists for cognitive dysfunction: A review of animal studies . Frontiers in Bioscience 13 : 2614 – 2632 . 17981738
49 Dall'lgna OP , Porciúncula LO , Souza DO , Cunha RA , Lara DR ( 2003 ) Neuroprotection by caffeine and adenosine A2A receptor blockade of β-amyloid neurotoxicity . British Journal of Pharmacology 138 : 1207 – 1209 . 12711619
50 Canas PM , Porciuncula LO , Cunha GM , Silva CG , Machado NJ , et al ( 2009 ) Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway . J Neurosci 29 : 14741 – 14751 . 19940169
51 Stone TW ( 2002 ) Purines and neuroprotection . Adv Exp Med Biol 513 : 249 – 280 . 12575824
52 Klein AM , Kowall NW , Ferrante RJ ( 1999 ) Neurotoxicity and oxidative damage of beta amyloid 1-42 versus beta amyloid 1–40 in the mouse cerebral cortex . Ann N Y Acad Sci 893 : 314 – 320 . 10672257
53 Lee RK , Araki W , Wurtman RJ ( 1997 ) Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation . Proc Natl Acad Sci U S A 94 : 5422 – 5426 . 9144253
54 Kumar A , La Rosa FG , Hovland AR , Cole WC , Edwards-Prasad J , et al ( 1999 ) Adenosine 3′,5′-cyclic monophosphate increases processing of amyloid precursor protein (APP) to beta-amyloid in neuroblastoma cells without changing APP levels or expression of APP mRNA . Neurochem Res 24 : 1209 – 1215 . 10492515
55 Su Y , Ryder J , Ni B ( 2003 ) Inhibition of Abeta production and APP maturation by a specific PKA inhibitor . FEBS Lett 546 : 407 – 410 . 12832078
56 Lu M , Liu Y-H , Ho CY , Tiong CX , Bian J-S ( 2012 ) Hydrogen sulfide regulates cAMP homeostasis and renin degranulation in As4.1 and rat renin-rich kidney cells . American Journal of Physiology - Cell Physiology 302 : C59 – C66 . 21940660
57 Lim JJ , Liu Y-H , Khin ESW , Bian J-S ( 2008 ) Vasoconstrictive effect of hydrogen sulfide involves downregulation of cAMP in vascular smooth muscle cells . American Journal of Physiology - Cell Physiology 295 : C1261 – C1270 . 18787076
58 Kimura H ( 2000 ) Hydrogen sulfide induces cyclic AMP and modulates the NMDA receptor . Biochem Biophys Res Commun 267 : 129 – 133 . 10623586
59 Defer N , Best-Belpomme M , Hanoune J ( 2000 ) Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase . American Journal of Physiology - Renal Physiology 279 : F400 – F416 . 10966920
60 Yang HY, Wu ZY, Wood M, Whiteman M, Bian JS (2013) Hydrogen Sulfide Attenuates Opioid Dependence by Suppression of Adenylate Cyclase/cAMP Pathway. Antioxid Redox Signal.
61 Xia W , Zhang J , Kholodenko D , Citron M , Podlisny MB , et al ( 1997 ) Enhanced Production and Oligomerization of the 42-residue Amyloid β-Protein by Chinese Hamster Ovary Cells Stably Expressing Mutant Presenilins . Journal of Biological Chemistry 272 : 7977 – 7982 . 9065468
62 Haass C , Lemere CA , Capell A , Citron M , Seubert P , et al ( 1995 ) The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway . Nat Med 1 : 1291 – 1296 . 7489411
63 Chen Y , Zhao J , Du J , Xu G , Tang C , et al ( 2012 ) Hydrogen sulfide regulates cardiac sarcoplasmic reticulum Ca2 + uptake via KATP channel and PI3K/Akt pathway . Life Sciences 91 : 271 – 278 . 22884808
64 Zhang H , Gao Y , Zhao F , Dai Z , Meng T , et al ( 2011 ) Hydrogen sulfide reduces mRNA and protein levels of beta-site amyloid precursor protein cleaving enzyme 1 in PC12 cells . Neurochem Int 58 : 169 – 175 . 21095213
65 De Strooper B ( 2003 ) Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex . Neuron 38 : 9 – 12 . 12691659
66 St George-Hyslop PH ( 2000 ) Molecular genetics of Alzheimer's disease . Biological psychiatry 47 : 183 – 199 . 10682216
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
오픈액세스 학술지에 출판된 논문
※ AI-Helper는 부적절한 답변을 할 수 있습니다.