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Piper sarmentosum Roxb. confers neuroprotection on beta-amyloid (Aβ)-induced microglia-mediated neuroinflammation and attenuates tau hyperphosphorylation in SH-SY5Y cells

Journal of ethnopharmacology, v.217, 2018년, pp.187 - 194  

Yeo, Emilia Tze Ying (School of Pharmacy, International Medical University, No. 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia) ,  Wong, Kelly Wang Ling (School of Pharmacy, International Medical University, No. 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia) ,  See, Mun Ling (School of Pharmacy, International Medical University, No. 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia) ,  Wong, Ka Yan (School of Pharmacy, International Medical University, No. 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia) ,  Gan, Sook Yee (School of Pharmacy, International Medical University, No. 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia) ,  Chan, Elaine Wan Ling (Institute for Research, Development and Innovation, International Medical University, No. 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000 Kuala Lumpur, Malaysia)

Abstract AI-Helper 아이콘AI-Helper

Abstract Ethnopharmacological relevance Piper sarmentosum Roxb. (PS), belonging to Piperaceae family, is an edible plant with medicinal properties. It is traditionally used by the Malays to treat headache and boost memory. Pharmacological studies revealed that PS exhibits anti-inflammatory, anti-o...

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참고문헌 (38)

  1. Lipids Health Dis. Amran 10 2 2011 10.1186/1476-511X-10-2 Changes in the vascular cell adhesion molecule-1, intercellular adhesion molecule-1 and c-reactive protein following administration of aqueous extract of Piper sarmentosum on experimental rabbits fed with cholesterol diet 

  2. Oxid. Med Cell Longev. Balez 2016 3806157 2016 10.1155/2016/3806157 Getting to NO Alzheimer's Disease: neuroprotection versus neurotoxicity mediated by nitric oxide 

  3. Neuron Bhaskar 68 19 2010 10.1016/j.neuron.2010.08.023 Regulation of tau pathology by the microglial fractalkine receptor 

  4. Neurology Buerger 59 627 2002 10.1212/WNL.59.4.627 CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects 

  5. Int. J. Neurosci. Cai 124 307 2014 10.3109/00207454.2013.833510 Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer's disease 

  6. Food Chem. Chanwitheesuk 92 491 2005 10.1016/j.foodchem.2004.07.035 Screening of antioxidant activity and antioxidant compounds of some edible plants of Thailand 

  7. Curr. Alzheimer Res. Domingues 14 870 2017 10.2174/1567205014666170317113606 Impact of cytokines and chemokines on Alzheimer's disease neuropathological hallmarks 

  8. J. Neurosci. Off. J. Soc. Neurosci. Ghosh 33 5053 2013 10.1523/JNEUROSCI.4361-12.2013 Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model 

  9. J. Zhejiang Univ. Sci. B Hafizah 11 357 2010 10.1631/jzus.B0900397 Piper sarmentosum as an antioxidant on oxidative stress in human umbilical vein endothelial cells induced by hydrogen peroxide 

  10. PLoS One Hematpoor 11 e0155265 2016 10.1371/journal.pone.0155265 Inhibition and larvicidal activity of phenylpropanoids from Piper sarmentosum on acetylcholinesterase against mosquito vectors and their binding mode of interaction 

  11. Chil. J. Agric. Res. Henriquez 70 523 2010 10.4067/S0718-58392010000400001 Determination of antioxidant capacity, total phenolic content and mineral composition of different fruit tissue of five apple cultivars grown in Chile 

  12. Plos One Hummel 2016 2016 No Overt Deficits in Aged Tau-deficient C57BI/6. Mapttm1(EGFP)Kit GFP Knockin Mice 

  13. Planta Med. Hussain 76 418 2010 10.1055/s-0029-1186279 Standardization and in vivo antioxidant activity of ethanol extracts of fruit and leaf of Piper sarmentosum 

  14. Am. J. Pathol. Janelsins 173 1768 2008 10.2353/ajpath.2008.080528 Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice 

  15. Afr. J. Biotechnol. Kamilolu 8 303 2009 Total phenolics and antioxidant activity of jujube (Zizyphus jujube Mill.) genotypes selected from Turkey 

  16. APCBEE Procedia Khan 2 199 2012 10.1016/j.apcbee.2012.06.035 Anti-acetylcholinesterase activity of Piper sarmentosum by a continuous immobilized-enzyme assay 

  17. Molecules Kim 4 23 2018 Modulation of inducible nitric oxide synthase expression in LPS-stimulated BV-2 microglia by prenylated chalcones from Cullen corylifolium (L.) Medik. Through inhibition of I-κBα degradation 

  18. J. Immunol. Kitazawa 187 6539 2011 10.4049/jimmunol.1100620 Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model 

  19. J. Neuroimmunol. Kuno 162 89 2005 10.1016/j.jneuroim.2005.01.015 Autocrine activation of microglia by tumor necrosis factor-alpha 

  20. J. Neuroinflamm. Lee 7 56 2010 10.1186/1742-2094-7-56 LPS-induced inflammation exacerbates phospho-tau pathology in rTg4510 mice 

  21. Asian-Australas. J. Anim. Sci. Lee 27 1461 2014 10.5713/ajas.2013.13629 Investigation on antibacterial and antioxidant activities, phenolic and flavonoid contents of some Thai edible plants as an alternative for antibiotics 

  22. J. Ethnopharmacol. Li 199 9 2017 10.1016/j.jep.2017.01.037 Piper sarmentosum Roxb. produces antidepressant-like effects in rodents, associated with activation of the CREB-BDNF-ERK signaling pathway and reversal of HPA axis hyperactivity 

  23. Ageing Res. Rev. Liu 0 6 2014 10.1016/j.arr.2013.12.007 The role of inflammasome in Alzheimer's disease 

  24. Front. Neurosci. Maphis 9 196 2015 10.3389/fnins.2015.00196 Loss of tau rescues inflammation-mediated neurodegeneration 

  25. Front Integr. Neurosci. Meraz-Rios 7 59 2013 10.3389/fnint.2013.00059 Inflammatory process in Alzheimer's disease 

  26. Mt. Sinai J. Med. Metcalfe 77 50 2010 10.1002/msj.20163 Relationship between tau pathology and neuroinflammation in Alzheimer's disease 

  27. BMC Complement. Altern. Med. Mohd Zainudin 15 54 2015 10.1186/s12906-015-0565-z The use of Piper sarmentosum leaves aqueous extract (Kadukmy™) as antihypertensive agent in spontaneous hypertensive rats 

  28. Mol. Neurodegener. Pan 6 45 2011 10.1186/1750-1326-6-45 Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease 

  29. J. Anal. Pharm. Res. Rahman 2 2016 Piper sarmentosum Roxb.: a mini review of ethnobotany, phytochemistry and pharmacology 

  30. Songklanakarin J. Sci. Technol. Ridtitid 29 1519 2007 Studies of the anti-inflammatory and antipyretic activities of the methanolic extract of Piper sarmentosum Roxb. leaves in rats 

  31. Brain Res. Shi 1368 239 2011 10.1016/j.brainres.2010.10.053 Anti-TNF-α reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains 

  32. Mol. Neurobiol. Sochocka 54 8071 2017 10.1007/s12035-016-0297-1 Inflammatory response in the CNS: friend or foe? 

  33. Ann. Transl. Med. Wang 3 136 2015 Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease 

  34. J. Neuroinflamm. Wilkaniec 15 1 2018 10.1186/s12974-017-1027-y Inhibition of cyclin-dependent kinase 5 affects early neuroinflammatory signalling in murine model of amyloid beta toxicity 

  35. Neuron Yoshiyama 53 337 2007 10.1016/j.neuron.2007.01.010 Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model 

  36. Front. Cell Neurosci. Yuste 9 322 2015 10.3389/fncel.2015.00322 Implications of glial nitric oxide in neurodegenerative diseases 

  37. J. Ethnopharmacol. Zakaria 128 42 2010 10.1016/j.jep.2009.12.021 In vivo anti-nociceptive and anti-inflammatory activities of the aqueous extract of the leaves of Piper sarmentosum 

  38. J. Ethnopharmacol. Zhai 194 153 2016 10.1016/j.jep.2016.09.013 Corydalis bungeana Turcz. Attenuates LPS-induced inflammatory response via the suppression of NF-κB signalling pathway in vitro and in vivo 

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