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NTIS 바로가기Communications biology, v.2, 2019년, pp.2 -
Thi Tran, Uyen (YCI Laboratory for Cellular Bioenergetic Network, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045 Japan) , Kitami, Toshimori (YCI Laboratory for Cellular Bioenergetic Network, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045 Japan)
The NLRP3 inflammasome is unique among pattern recognition receptors in using changes in cellular physiology as a mechanism for sensing host danger. To dissect the physiological network controlling inflammasome activation, we screened for small-molecule activators and suppressors of IL-1β relea...
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