치료 실시중 세균의 항생제 내성 발현은 임상 분야의 중요한 문제점중 하나인데 중요한 원인중 하나는 원인세균의 분리와 그에 따른 항생제 감수성 검사 결과에 바탕을 두지 않은 무분별하며 적절치 않은 항생제를 선택함에 있다. 따라서 본 연구에서는 대학동물 병원에 내원한 임상증례로부터 채취한 임상검체에서 협기성 세균을 분리 동정하고 항생제 감수성 양상을 검사하고자 하였다. 이를 위해 2001년 5월부터 2002년 10월까지 서울대학교 동물병원에 내원한 개, 고양이 및 토끼로부터 채취한 임상검체에 대해 협기성 배양을 실시하고 분리 동정된 세균에 대해서는 표준 디스크 검사법을 이용해 항생제 감수성을 평가하였다. 총 13주; Bacteroidesspp. (3주), Fusobacterium spp. (2주), Peptostreptococcus spp. (2주), Porphyromonas gingivalis (2주), Prevotella spp. (3주), Propionibacterium acnes (1주)의 혐기성 세균이 분리동정 되었으며 항생제 감수성 검사에서는 Fusobucterium varium 1주만이 norfloxacin 에 저항성을 나타내었으나 그 외 모든 분리주가 검사대상 항생제에 대한 감수성이 있는 것으로 나타났다.
치료 실시중 세균의 항생제 내성 발현은 임상 분야의 중요한 문제점중 하나인데 중요한 원인중 하나는 원인세균의 분리와 그에 따른 항생제 감수성 검사 결과에 바탕을 두지 않은 무분별하며 적절치 않은 항생제를 선택함에 있다. 따라서 본 연구에서는 대학동물 병원에 내원한 임상증례로부터 채취한 임상검체에서 협기성 세균을 분리 동정하고 항생제 감수성 양상을 검사하고자 하였다. 이를 위해 2001년 5월부터 2002년 10월까지 서울대학교 동물병원에 내원한 개, 고양이 및 토끼로부터 채취한 임상검체에 대해 협기성 배양을 실시하고 분리 동정된 세균에 대해서는 표준 디스크 검사법을 이용해 항생제 감수성을 평가하였다. 총 13주; Bacteroidesspp. (3주), Fusobacterium spp. (2주), Peptostreptococcus spp. (2주), Porphyromonas gingivalis (2주), Prevotella spp. (3주), Propionibacterium acnes (1주)의 혐기성 세균이 분리동정 되었으며 항생제 감수성 검사에서는 Fusobucterium varium 1주만이 norfloxacin 에 저항성을 나타내었으나 그 외 모든 분리주가 검사대상 항생제에 대한 감수성이 있는 것으로 나타났다.
The emergence of bacterial resistance to antibiotics during therapy is a matter of great problem in clinical medicine. This may be because many veterinarians have used inappropriate antibiotics without bacteriological culture. Therefore, the purpose of this study is to determine isolation of anaerob...
The emergence of bacterial resistance to antibiotics during therapy is a matter of great problem in clinical medicine. This may be because many veterinarians have used inappropriate antibiotics without bacteriological culture. Therefore, the purpose of this study is to determine isolation of anaerobic bacteria as pathogens from veterinary clinical specimens as well as susceptibility pattern for choosing antibiotics. Various anaerobic bacteria were isolated from clinical specimens of dogs, cats, rabbits at Veterinary Medical Teaching Hospital of Seoul National University from May 2001 to October 2002. The total number of isolated anaerobic bacteria was 13 isolates; Bacteroides spp. (3 isolates), Fusobacterium spp. (2 isolates), Peptostreptococcus spp. (2 isolates), Porphyromonas gingivalis (2 isolates), Prevotella spp. (3 isolates), and Propionibacterium acnes (1 isolate). For evaluating the antibiotic susceptibility patterns of the isolates disk diffusion method was used. All isolates were susceptable to all tested antibiotics except only one Fusobacterium varium was resistant to norfloxacin.
The emergence of bacterial resistance to antibiotics during therapy is a matter of great problem in clinical medicine. This may be because many veterinarians have used inappropriate antibiotics without bacteriological culture. Therefore, the purpose of this study is to determine isolation of anaerobic bacteria as pathogens from veterinary clinical specimens as well as susceptibility pattern for choosing antibiotics. Various anaerobic bacteria were isolated from clinical specimens of dogs, cats, rabbits at Veterinary Medical Teaching Hospital of Seoul National University from May 2001 to October 2002. The total number of isolated anaerobic bacteria was 13 isolates; Bacteroides spp. (3 isolates), Fusobacterium spp. (2 isolates), Peptostreptococcus spp. (2 isolates), Porphyromonas gingivalis (2 isolates), Prevotella spp. (3 isolates), and Propionibacterium acnes (1 isolate). For evaluating the antibiotic susceptibility patterns of the isolates disk diffusion method was used. All isolates were susceptable to all tested antibiotics except only one Fusobacterium varium was resistant to norfloxacin.
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문제 정의
In this study, we report anaerobic bacteria isolated from animal patients in Veterinary Medical Teaching Hospital of Seoul National University as well as susceptibility pattern. The purpose of this study is the isolation of anaerobic bacteria as pathogens.
Prevotella and Porphyromonas species were frequently isolated from the oral cavity of animals415, 16. Porphyromonas gingivalis was isolated from tracheal washing of the dog with chronic respiratory disease in this study. The usual source of bacteria in anaerobic lung infections is the oral cavity-presumably the gingival crevice13, 22.
This study emphasized the need for the isolation of anaerobic bacteria as pathogens in order to select appropriate antibiotics. To select appropriate antibiotics may be helpful to reduce antibiotic resistance and to treat animal patients.
제안 방법
In this study, we report anaerobic bacteria isolated from animal patients in Veterinary Medical Teaching Hospital of Seoul National University as well as susceptibility pattern. The purpose of this study is the isolation of anaerobic bacteria as pathogens.
대상 데이터
This study shows the involvement of 13 strains of anaerobic bacteria. These came from 9 dogs, 3 rabbits and 1 cat.
This study shows the involvement of 13 strains of anaerobic bacteria. These came from 9 dogs, 3 rabbits and 1 cat. These animal patients have suffered from chronic diseases although they have been treated with antibiotics which were focused on aerobic bacteria for a long time.
이론/모형
The susceptibility test of isolates was determined by the disk diffusion method. Bacterial suspension of the anaerobic isolate (McFarland 0.
The susceptibility test of anaerobic isolates was executed by disk diffusion method. Only one strain of Fusobacterium varium was resistant to norfloxacin in this study.
성능/효과
Additional information, routine susceptibility testing of anaerobic isolates is not recommended21. In this study, there was not significant for anaerobic susceptibility, because the total number of isolated anaerobic bacteria was low and the distribution of those bacteria was variable. Also, anaerobic susceptibility test is not being performed routinely in human medicine in Korea, because of low resistance.
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