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논문 상세정보

기능성 소화불량증 환자에 대한 한약복합제의 치료 효과: 무작위배정 표준치료제 위약 대조군 연구

Effect of Herb Medicine Treatment for Functional Dyspepsia: A Randomized Placebo-Controlled and Compared Standard Treatment Trial

Abstract

Objective: Functional dyspepsia is a prevalent disease. It impedes subjective quality of life. The purpose of this study was to examine the equivalent effect of herb medicine treatment (DA-9701) for functional dyspepsia. Methods: In this randomized, single-blinded, placebo-controlled study, we compared a herb medicine (DA-9701) with standard treatment (mosapride) and placebo for the treatment of functional dyspepsia. 42 volunteers who satisfied the requirements were enrolled in study. Severity of dyspepsia was measured by Nepean Dyspepsia Index (NDI) and Functional Dyspepsia Quality of Life (FD-QOL) before and after treatments. Results: 1. In the DA-9701 group, total key symptoms score was significantly lower and improve rate of key symptoms was higher than in the mosapride and placebo groups, but there were no statistically significant differences between three groups. 2. In the DA-9701 and mosapride groups, "nausea" and "bad breath" were significantly lower compared with the placebo group. 3. In the DA-9701 group, NDI Quality of Life scores were significantly higher, but there were no [other] statistically significant differences between the three groups. 4. In the DA-9701 and mosapride groups, FD-QOL scores were higher compared with the placebo group, but there were no statistically significant differences between the three groups. Conclusion: Herb medicine treatment (DA-9701) is effective to improve the symptoms and quality of life in patients with functional dyspepsia.

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이 논문을 인용한 문헌 (2)

  1. Kim, Yun-Young ; Yoo, Jong-Hyang ; Lee, Su-Kyung ; Lee, Si-Woo 2011. "Quality Assessment of Randomized Controlled Trials using Herbal Remedies in Korea" 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine, 25(5): 927~933 
  2. Bae, Su-Hyun ; Park, Seon-Young ; Jin, Myung-Ho ; Park, Sang-Eun ; Hong, Sang-Hoon 2012. "Case Study of Western-Oriental Medication Combination Treatment for Helicobacter pylori Infection" 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine, 26(3): 381~385 

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