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NTIS 바로가기한국현미경학회지 = Korean journal of microscopy, v.41 no.3, 2011년, pp.197 - 204
이경옥 (호원대학교 미용예술학과) , 김영철 (계명대학교 대학원 공중보건학과) , 장병수 (한서대학교 보건학부 피부미용학과)
To investigate the alleviative effect of white tea water extract on the inflammation and skin barrier damage, skin aging animal model was produced by the irradiation of UVB to the backs of hairless mice for 12 weeks. And then experimental materials were applied topically for 4 weeks. At the 28th day...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
자외선 조사는 무엇을 일으키는가? | 자외선 조사는 주름, 일광화상, 면역억제, 암과 같은 다양한 피부변화를 일으키며, 피부 결합조직에 주로 발생하는 광 손상은 광노화의 특징적인 형태를 나타낸다(Fisher et al., 1997). | |
자외선에 노출된 피부에서는 무엇이 생성되는가? | , 1997). 자외선에 노출된 피부에서는 O2-∙, OH∙, RO2∙, H2O2와 같은 활성산소종(reactive oxygen species, ROS)이 다량 생성된다(Cerutti, 1991). 생체내에서 활성산소종은 에너지 생산과 식균작용, 세포성장과 세포내 신호조절과 같은 긍정적인 역할을 하는 반면, 핵산, 단백질, 지방산과 당류와 반응하여 산화적 손상을 초래하기도 하며, 이러한 산화적 손상의 영향으로 세포 대사교란, 형태학적 및 초미세 구조 변화 등 (Svobodova et al. | |
기능성 물질 중 retinoids는 어떤 기능을 하는가? | 현재까지 피부노화 억제 및 개선을 위한 많은 연구가 진행되고 있으며 기능성 물질들이 다양하게 개발되어 사용되고 있다. 그 중 retinoids는 각질형성세포와 섬유아세포의 증식을 유도하고 진피에서 콜라겐 합성을 촉진하는 것으로 알려져 있다(Varani et al., 1991). |
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