최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Korean journal of acupuncture, v.31 no.4, 2014년, pp.147 - 157
양미성 (동신대학교 한의과대학 한방재활의학과) , 김선종 (동신대학교 한의과대학 한방재활의학과) , 최진봉 (동신대학교 한의과대학 한방재활의학과)
Objectives : The purpose of this study is to explore the current research trend on acupuncture treatment for nerve regeneration and recovery effect. Methods : We investigated the researches so far, on acupuncture treatment for the nerve regeneration and recovery via searching Pubmed from 2005 up to ...
* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.
핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
말초 신경의 손상이란 무엇인가? | 말초 신경의 손상은 뇌, 척수의 중추신경계를 제외한 나머지 신경계의 손상을 통틀어 이르는 용어로 마찬가지로 외상이나 질병, 대사 장애, 약물, 독소, 유전적 원인 등 다양한 원인에 의해 손상될 수 있다. 말초 신경 손상의 경우, 느리더라도 축삭의 느린 재생을 동반하여 회복을 일으키고 5) , 중추 신경계의 손상 또한 신경 재생이 불가능하다고 여겼던 과거와 달리, 신경가소성에 의해 신경재활이 가능하다고 여겨지고 있다 6) . | |
신경계는 어떻게 나눌 수 있는가? | 신경계는 크게 뇌, 척수를 포함하는 중추 신경계(Central Nervous System; CNS)와 말초 신경계(Peripheral Nervous System; PNS)로 나눌 수 있다. 이러한 신경계는 노화, 질병, 상해 등에 의해 손상되기도 하는데 자연적, 혹은 약물을 이용한 재생이 힘들고 이에 따라 치유가 어렵거나 후유증이 남는 경우가 많다 1) . | |
최근 신경재생에 대한 근본적 치료는 어떠한 상황인가? | 그러나 중추 신경이든, 말초 신경이든, 일단 손상된 후에 근본적 이고 완전한 신경의 재생을 일으키는 치료는 현재까지 딱히 없는데 일례로, 서양의학에서 척수손상의 치료는 수술 및 스테로이드 약물을 이용한 합병증 방지와 기능회복이 주가 되며 치료 결과는 만족할 만한 수준은 못되는 것으로 평가된다 7,8) . 최근 줄기세포를 이용 하거나 신경성장인자를 투여하고 축삭의 성장을 돕는 세포 이식 방법이 활용되고 있으나 아직은 널리 상용화되지는 못하고 있다 9) |
Cho MS, Lee HS, Kim MH. Application of Human Embryonic Stem Cells for Neural Disease. Tissue Engineering and Regenerative medicine. 2007 ; 4(2) : 159-62.
Barnett HJ, Eliasziw M, Meldrum HE. Evidence based cardiology: prevention of ischemic stroke. BMJ. 1999 ; 318(7197) : 1539-43.
Korea Geriatrics Society. Geriatrics Medicine. Seoul: Medical Publisher. 2002 : 67-71.
Kim DA, Lee BS, Kim EJ, Choi H. Epidemiological analysis of the spinal cord disabilities 16 years admitted to the National Rehabilitation Center. Research report about Quality of life in Korea spinal cord disabilities. National Rehabilitation Center 2012.
Ide C. Peripheral nerve regeneration. Neuroscience res. 1996 ; 25 : 101-21.
TJ Coderre, J Katz, AL Vaccarino, R Melzack. Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain, 1993 ; 52(3) : 259-85.
Lee KH, Yoon DH, Park YG, Lee BH. Effects of glial transplantation on functional recovery following acute spinal cord injury. J Neurotrauma. 2005 ; 22(5) : 575-89.
Yang MS, Kee YB, Kang DH, Shin MS , Kim SJ, Choi JB. The Effects of ST36, GB34, GB39 and Hyeopcheok Points on Nerve Regeneration in Spinal Cord Injury Rat Model. J Oriental Rehab Med. 2012 ; 22(4) : 1-21.
Ahn HL ,Yang MS, Shin MS, Choi JB, Kim SJ. The Experimental Study of Electroacupuncture and CerviPantortichum Cornu Pharmacopuncture on Pain Decrease and Nerve Regeneration after Crush Injury of Sciatic NerveJ Oriental Rehab Med. 2009 ; 19(1) : 39-55.
Sul JU, Chu MK, Kim SJ, Choi JB, Shin MS, Kim Soo-Ik. Effects of Yanghyuljanggeungunbo-tang(Yangxuezhuangjinjianbu-tang) and Electrical Acupuncture on the Spinal Nerve Injury and the Motor Function. J Oriental Rehab Med. 2009 ; 19(2) : 1-25.
Choi JH, Min KO, Kim SH, Kim DI, Lee SB, An HJ, et al. A Study on the Effects of the Electro-Acupuncture(EA) Stimulation after Global Ischemia(GI) on Changes in Bax and Caspase-3 Expression among Forebrain Apoptosis. J. of Oriental Neuropsychiatry 2010 ; 21(1) : 59-69.
Zhou H, Sun G, Kong L, Du Y, Shen F, Wang S, et al. Acupuncture and moxibustion reduces neuronal edema in Alzheimer's disease rats. Neural Regen Res. 2014 ; 9(9) : 968-72.
Zhang R, Cai X, Song X, Dong C, Hou X, Lv L. Normalization of ventral tegmental area structure following acupuncture in a rat model of heroin relapse. Neural Regen Res. 2014 ; 9(3) : 301-7.
Hou X, Zhang R, Lv H, Cai X, Xie G, Song X. Acupuncture at Baihui and Dazhui reduces brain cell apoptosis in heroin readdicts. Neural Regen Res. 2014 ; 9(2) : 164-70.
Wang SJ, Fang JQ, Ma J, Wang YC, Liang SR, Zhou D, et al. Electroacupuncture-regulated neurotrophic factor mRNA expression in the substantia nigra of Parkinson's disease rats. Neural Regen Res. 2013 ; 8(6) : 540-9.
Huang SF, Ding Y, Ruan JW, Zhang W, Wu JL, He B, et al. An experimental electro-acupuncture study in treatment of the rat demyelinated spinal cord injury induced by ethidium bromide. Neurosci Res. 2011 ; 70(3) : 294-304.
Li WJ, Pan SQ, Zeng YS, Su BG, Li SM, Ding Y, et al. Identification of acupuncture-specific proteins in the process of electro- acupuncture after spinal cord injury. Neurosci Res. 2010 ; 67(4) : 307-16.
Chen J, Qi JG, Zhang W, Zhou X, Meng QS, Zhang WM, et al. Electro-acupuncture induced NGF, BDNF and NT-3 expression in spared L6 dorsal root ganglion in cats subjected to removal of adjacent ganglia. Neurosci Res. 2007 ; 59(4) : 399-405.
Sun YJ, Wu YC, Zhang JF, Zhang P, Tang ZY. Effects of electroacupuncture on muscle state and electrophysiological changes in rabbits with lumbar nerve root compression. Chin J Integr Med. 2013 ; 19(6) : 446-52.
Liu ZH, Qi YC, Pan PG, Ma MM, Qian XG, Fu WJ. Clinical observation on treatment of clearing the Governor Vessel and refreshing the mind needling in neural development and remediation of children with cerebral palsy. Chin J Integrative Medicine. 2013 ; 19(7) : 505-9.
Inoue M, Katsumi Y, Itoi M, Hojo T, Nakajima M, Ohashi S, et al. Direct current electrical stimulation of acupuncture needles for peripheral nerve regeneration: an exploratory case series. Acupunct Med. 2011 ; 29(2) : 88-93.
Kim MW, Chung YC, Jung HC, Park MS, Han YM, Chung YA, et al. Electroacupuncture enhances motor recovery performance with brain-derived neurotrophic factor expression in rats with cerebral infarction. Acupunct Med. 2012 ; 30(3) : 222-6.
Kim WS, Kim IS, Kim SJ, Wei PF, Choi DH, Han TR. Effect of electroacupuncture on motor recovery in a rat stroke model during the early recovery stage. Brain Research. 2009 ; 1248 : 176-83.
Pagani L, Manni L, Aloe L. Effects of electroacupuncture on retinal nerve growth factor and brain-derived neurotrophic factor expression in a rat model of retinitis pigmentosa. Brain Res. 2006 ; 1092(1) : 198-206.
Choi DC, Lee JY, Moon YJ, Kim SW, Oh TH, Yune TY. Acupuncture- mediated inhibition of inflammation facilitates significant functional recovery after spinal cord injury. Neurobiol Dis. 2010 ; 39(3) : 272-82.
Kim YR, Kim HN, Ahn SM, Choi YH, Shin HK, Choi BT. Electroacupuncture promotes post-stroke functional recovery via enhancing endogenous neurogenesis in mouse focal cerebral ischemia. PLoS One. 2014 ; 9(2) : e90000.
Ding Y, Yan Q, Ruan JW, Zhang YQ, Li WJ, Zeng X, et al. Bone marrow mesenchymal stem cells and electroacupuncture downregulate the inhibitor molecules and promote the axonal regeneration in the transected spinal cord of rats. Cell Transplant. 2011 ; 20(4) : 475-91.
Yan Q, Ruan JW, Ding Y, Li WJ, Li Y, Zeng YS. Electro-acupuncture promotes differentiation of mesenchymal stem cells, regeneration of nerve fibers and partial functional recovery after spinal cord injury. Exp Toxicol Pathol. 2011 ; 63(1-2) : 151-6.
Ding Y, Yan Q, Ruan JW, Zhang YQ, Li WJ, Zhang YJ, et al. Electro-acupuncture promotes survival, differentiation of the bone marrow mesenchymal stem cells as well as functional recovery in the spinal cord-transected rats. BMC Neurosci. 2009 ; 20 ; 10 : 35.
Li WJ, Li SM, Ding Y, He B, Keegan J, et al. Electro-acupuncture upregulates CGRP expression after rat spinal cord transection. Neurochem Int. 2012 ; 61(8) : 1397-403.
Wang TT, Yuan Y, Kang Y, Yuan WL, Zhang HT, Wu LY, et al. Effects of acupuncture on the expression of glial cell line-derived neurotrophic factor(GDNF) and basic fibroblast growth factor(FGF-2/bFGF) in the left sixth lumbar dorsal root ganglion following removal of adjacent dorsal root ganglia. Neurosci Lett. 2005 ; 382(3) : 236-41.
Wang TH, Wang XY, Li XL, Chen HM, Wu LF. Effect of electroacupuncture on neurotrophin expression in cat spinal cord after partial dorsal rhizotomy. Neurochem Res. 2007 ; 32(8) : 1415-22.
La JL, Jalali S, Shami SA. Morphological studies on crushed sciatic nerve of rabbits with electroacupuncture or diclofenac sodium treatment. Am J Chin Med. 2005 ; 33(4) : 663-9.
Ho CY, Yao CH, Chen WC, Shen WC, Bau DT. Electroacupuncture and Acupuncture Promote the Rat's Transected Median Nerve Regeneration. Evid Based Complement Alternat Med. 2013 ; 2013 : 514610.
Schroder S, Liepert J, Remppis A, Greten JH. Acupuncture treatment improves nerve conduction in peripheral neuropathy. Eur J Neurol. 2007 ; 14(3) : 276-81.
Manni L, Albanesi M, Guaragna M, Barbaro Paparo S, Aloe L. Neurotrophins and acupunctures. Auton Neurosci. 2010 ; 157(1-2) : 9-17.
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
오픈액세스 학술지에 출판된 논문
※ AI-Helper는 부적절한 답변을 할 수 있습니다.