최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine, v.28 no.4, 2014년, pp.403 - 410
The purpose of this study was to examine the anti-depressive effects of OnDam-Tang with addition of Linderae Radix (ODT-L) on the animal model of depression induced by chronic immobilization stress. Depression model was made by chronic immobilization stress for 2 hours for 21 days. And we performed ...
* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.
핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
우울증의 원인은 무엇인가? | 우울증의 원인은 유전적 요인, 생물학적 요인, 심리사회적 요인들이 복합적으로 작용할 것으로 추정되며, 신체질환이나 약물에 의해서도 발병할 수 있다1). 모노아민 가설은 monoamine 특히 norepinephrine 이나 serotonin 활성도 감소가 우울증의 발병에 중요한 역할을 한다는 가설로, 우울증의 발생과 관련된 가설 중가장 잘 알려진 이론이다5) | |
우울증이란? | 우울증은 우울한 기분, 흥미의 감소, 식욕 및 체중 변화, 불면 또는 과수면, 무가치감 등의 증상들로 이루어진 일련의 증후군으로, 반복되는 재발 삽화가 특징적인 질환이다1) | |
우울증의 평생유병률은 어느정도인가? | 평생유병률이 약 10% 정도로 매우 흔한 질환일 뿐 만 아니라, 높은 재발률이 특징으로 2년 후 재발률이 25-40%이고 점차 재발률이 증가해서 5년 후에는 60%, 10년 후에는 75%, 15년 후에는 87%에 이른다고 알려져 있다2). 이러한 높은 재발률은 우울증으로 인해 발생하는 막대한 규모의 사회경제적 비용손실의 원인이 된다3). |
The Textbook Compliation Committee of Neuropshychiatry of Oriental Schools in Nation. The Neuropsychiatry of Oriental Medicine. Seoul, Jipmoon-Dang, pp 472-475, 477-478, 2007.
Keller, M.B., Bolland, R.J. Implications of failing to achieve successful long-term maintenance treatment of recurrent unipolar major depressoion. Biological Psychiatry 44: 348-360, 1998.
Greenberg, P.E., Kessler, R., Birnbaum, H.G., Leong, S.A., Lowe, S.W., Berglund, P.A. The economic burden of depression in the United States: How did it change between 1990 and 2000. J Clin Psychiatry 64: 1465-1475, 2003.
Ministry for Health, Welfare and Family Affairs. The Epidemiological Survey of Mental Disorders in Korea, 2011.
Choi, E.M., Koo, S.J. Possibility of regulation by food in depression and mood disorders. Food science and industry, 34(4):53-69, 2001.
Lee, S.H., Kim, B.Y., Kee, J.I., Kwen, S.J., Chung, D.K. A case of Mixed anxiety and depressive disorder. Journal of oriental neuropsychiatry 14(2):127-134, 2003.
Kang, H.W., Jang, H.H., Kang, I.S., Moon, H.C., Hwang, Y.J., Lyu, Y.S. A Study on The Oriental-medical Understanding of Depression. Journal of oriental neuropsychiatry, 12(2):1-15, 2011.
Som, S.M. Bigeub cheon geum yo bang. Seoul, Daeseong munhwasa, p 217, 1984.
Seo, S.H., Jung, I.C., Lee, S.R. The Literature Study of Ondamtng, Guibitang, Soyosan & Their Gagambang Recording in Dong-Eui-Bo-Gam. Journal of institute of oriental medicine, Daejeon univ. 14(1):129-140, 2005.
Heo, J. Dong ui bo gam. Seoul, Beob-in munhwasa, p 238, 303, 428, 2005.
Eom, S.H. Experimental Study on the Effect of the Administration of Gamiondamtang on the Sleep Time. Master's Thesis of Graduate School of Kyunghee University, 1983.
Kim, C.D. Studies on Central Nervous Depressive Action of Ondam Tang Aqueous Extracts. Korean J Pharmacogn 12(1):66, 1981.
Kang, T.L. Effect of Gami-Ondamtang(GO) on brain neuronal transmitters in immobilized rats. Korean journal of oriental preventive medical society 5(2):114-121, 2001.
Kim, D.P., Choi, Y.S., Park, Y.H., Keum, D.H. A Case Report by Heart Rate Variability on the Patient with Dysfunction of Autonom ic Nervous System. Journal of oriental rehabilitation medicine 14(3):173-185, 2004.
Lim, J.M., Moon, B.S., Kim, S.G. Effects of Ondamtang Water Extract on the Heart Function. The Journal of Traditional Korean Medicine 3: 99-113, 1993.
Ju, Y.S. Ungok Herbology. Jeonju, Woosuk Press, p 827, 2013.
Voorhees, J.L., Tarr, A.J., Wohleb, E.S., Godbout, J.P., Mo, X., Sheridan, J.F., Eubank, T.D., Marsh, C.B. Prolonged Restraint Stress Increases IL-6, Reduces IL-10, and Causes Persistent Depressive-Like Behavior That Is Reversed by Recombinant IL-10. PLoS ONE 8(3):1-11, 2013.
Rodrigues, A.L., da Silva, G.L., Mateussi, A.S., Fernandes, E.S., Miguel, O.G., Yunes, R.A., Calixto, J.B., Santos, A.R. Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus. Life sciences 70(12):1347-1358, 2002.
Cryan, J.F., McGrath, C., Leonard, B.E., Norman, T.R. Combining Pindolol and Paroxetine in an Animal Model of Chronic Antidepressant Action. Can Early Onset of Action Be Detected? Eur J Pharmacol 352: 23-28, 1998.
Kang, S.S. Baleun Bangjehag. Seoul, Daeseong munhwasa, p 128, 1996.
Lucki, I. The spectrum of behaviors influenced by serotonin. Biol Psychiatry 44: 151-162, 1998.
Lee, H.S. Clinical Neuropsycopharmacology. Seoul, MLcommunication, 2009.
Koob, G.F. Corticotropin-releasing factor, Norepinephrine, and stress. Biol Psychiatry 46: 1167-1180, 1999.
Arborelius, L., Owens, M.J., Plotsky, P.M., Nemeroff, C.B. The role of corticotropin-releasing factor in depression and anxiety disorders. J Endocrin 160: 1-12, 1999.
Lee, K.W., Kang, S.K., Chun, Y.H., Hong, J.P. The Effect of Repeated Restraint Stress on Clusterin Change of the Rat Salivary Glands. The Journal of Korean Academy of Oral Medicine 37(2):81-91, 2012.
Ro, S.K. The Effect of Binding Stressed White Rats by Chijashitang and Chijashitang+Bambusea Caulis. Dept of Neuropsychiatry Graduate School Kyungsan University pp 1-36, 1995.
Yun, H.Y. Bupleurum Falcatum Prevents Depression Andanxiety-Like Behaviors in the Rats Exposed to Repeated Restraint Stress. Graduate School of Oriental Medicine KyungHee University pp 1-41, 2012.
Woon, F.L., Sood, S., Hedges, D.W. Hippocampal volume deficits associated with exposure to psychological trauma and posttraumatic stress disorder in adults: a meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry 34: 1181-1188, 2010.
Nestler, E.J., Barrot, M., DiLeone, R.J., Eisch, A.J., Gold, S.J., Monteggia, L.M. Neurobiology of depression. Neuron 34: 13-25, 2002.
McKinnon, M.C., Yucel, K., Nazarov, A., MacQueen, G.M.. A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder. J Psychiatry Neurosci 34: 41-54, 2009.
Lee, I.A., Yoganarasimha, D., Rao, G., Knierim, J.J. Comparison of population coherence of place cells in hippocampal subfields CA1 and CA3. Nature 430(6998):456-459, 2004.
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.