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NTIS 바로가기大韓韓方小兒科學會誌 = The journal of pediatrics of Korean medicine, v.31 no.3, 2017년, pp.14 - 23
안상현 (세명대학교 한의과대학 해부학교실) , 김기봉 (부산대학교 한의학전문대학원 한방소아과교실)
Objectives This study is conducted to evaluate skin fat barrier formation of Hataedock using the Coptis japonica & Glycyrrhiza uralensis extract. Methods The 3-week-old NC/Nga mice were divided into 3 groups: control group (Ctrl), Hataedock-treated group that uses the Coptis japonica & Glycyrrhiza u...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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황련과 감초의 효능은 각각 무엇인가? | 이중 황련과 감초를 사용한 하태독법이 있다. 황련 (黃連)은 청열조습 (淸熱燥濕), 사화해독 (瀉火解毒), 청심제번 (淸心除煩), 청열명목 (淸熱明目)하는 효능이 있으며15), 주요 활성성분인 berberine은 isoquinoline alkaloid계열로 항암16-18), 항바이러스19), 항균20) 작용 등의 약리 효능이 있다. 감초 (甘草)는 감평무독 (甘平無毒)하여 청열해독 (淸熱解毒), 윤폐지해 (潤肺止咳), 보비익기 (補脾益氣)하는 효능이 있으며, 간염이나 호흡기 질환, 소화기질환, 종양, 면역질환 등에 사용되었다21,22). 감초의 성분인 glycyrrhizin, liquiritin, liquiritigenin, isoliquiritigenin은 항균효과가 있다23,24). | |
각질층 구조체의 구성요소는 무엇인가? | 표피 (epidermis)는 체내의 수분을 지키고 항원이나 감염원 등의 외부 침입인자에 대한 일차적인 장벽기능 및 면역반응을 나타내는 피부장벽이다1,2). 표피의 장벽기능은 각질세포 (corneocyte), 각질세포외막 (cornifiedenvelope), 각질세포간 지질막 (lamellar membrane lipid, intercorneocyte lipid), 각질교소체 (corneodesmosome)로 구성된 각질층 구조체를 통해 일어난다3). 각질세포외막 중 각질세포 단백질외막 (cornified protein envelope)은 involucrin, loricrin, trichohyalin, small proline-rich proteins 등의 단백질 교차 결합으로 형성되어 물리적 장벽의 역할을 담당하게 되고4,5), 각질세포 지질외막(cornified lipid envelope)은 각질세포간 지질의 다중 층상 구조 형성을 유도하는 scaffold 역할을 하며 완전한 피부장벽구조를 형성하도록 한다6). | |
표피란? | 표피 (epidermis)는 체내의 수분을 지키고 항원이나 감염원 등의 외부 침입인자에 대한 일차적인 장벽기능 및 면역반응을 나타내는 피부장벽이다1,2). 표피의 장벽기능은 각질세포 (corneocyte), 각질세포외막 (cornifiedenvelope), 각질세포간 지질막 (lamellar membrane lipid, intercorneocyte lipid), 각질교소체 (corneodesmosome)로 구성된 각질층 구조체를 통해 일어난다3). |
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