[논문]수삼, 연질 홍삼, 수액 홍삼의 항산화 효과

허만규; 김국환

doi:10.5352/jls.2020.30.9.763

수삼, 연질 홍삼, 수액 홍삼의 항산화 효과
Antioxidant Effects of Raw Ginseng, Soft Red Ginseng, and Red Ginseng Sap 원문보기

생명과학회지 = Journal of life science, v.30 no.9, 2020년, pp.763 - 771

초록
AI-Helper

고려 인삼(Panax ginseng)은 일반적으로 안전성이 우수하고 ginsenosides or panaxosides 같은 많은 생활성적인 물질을 함유하고 있다. 특히 고려 홍삼은 교감 신경계를 안정시키고 인지력을 향상시키고 개인의 의학적 효과를 높이는 데 도움을 줄 수 있다. 새로운 가공 기술로 부드러운 홍삼을 생산하였다. 본 연구는 새로운 가공 기술에 따라 생산된 연질 홍삼이 항산화 효과를 감소시키거나 개선했는지 여부를 조사하는 데 초점을 맞췄다. 연질 홍삼과 시판 홍삼액은 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) 소거활성능에 있어 유의한 차이를 나타내지 않았다(p<0.05). 연질 홍삼은 수삼과 시판 홍삼액에 비해 DPPH (22-Diphenyl-1-pichrylic)와 OH(hydroxyl radical) 소거활성능이 높게 나타났다. OH 소거활성능은 세 그룹(수삼, 연질 홍삼과 시판 홍삼액) 간 유의한 차이를 나타내었다(p<0.05). NO (nitric oxide) 소거활성능 역시 수삼, 연질 홍삼, 홍삼 수액생산품 사이에 유의한 차이가 있었다(p<0.05). 연질 홍삼에서 많은 칼슘 결정체가 전자현미경상에서 관찰되었다. 마그네슘과 칼륨은 연질 홍상과 경질 홍삼 사이에 유의한 차이가 없었다. 연한 홍삼의 추출물은 DPPH와 OH의 존재로 인해 서로 다른 활성산소를 효율적으로 소거할 수 있어 자유 라디칼로 유도된 질환에 도움이 될 수 있다.

Abstract ▼ AI-Helper

Korean ginseng (Panax ginseng) generally has a good safety profile and contains many bioactive substances, such as ginsenosides or panaxosides. Korean red ginseng might help to stabilize the sympathetic nervous system and improve cognition in individuals. Soft red ginseng is produced by new processing technology. This study focused on investigating whether soft red ginseng produced under the new processing technology reduces or improves the existing antioxidant effects. No significant difference in 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) scavenging activity was found between soft red ginseng and ready-made red ginseng (p<0.05). Soft red ginseng extract showed higher 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) and hydroxyl radical (OH) scavenging activity than other ginseng extracts. OH scavenging activity was significantly different across three groups (raw ginseng, soft red ginseng, and red ginseng sap) (p<0.05). Nitric oxide (NO) scavenging activity was also significantly different among raw ginseng, soft red ginseng, and purchased red ginseng liquid products (p<0.05). Many calcium crystals appeared on the electron microscope in soft red ginseng. Magnesium and potassium showed no significant difference between soft red ginseng and hard red ginseng. The extract of soft red ginseng scavenged different free radicals efficiently due to the presence of DPPH and OH and may help treat free radical-induced diseases.

주제어

표/그림 (10)

표 Table 1. The degree of inhibition (%) of ABTS properties for raw ginseng, soft red ginseng, and ready-made red ginseng gap at different concentrations
표 Table 2. The 50% inhibition (EC₅₀) of ABTS on 1.0 ug/ml
표 Table 3. The degree of inhibition (%) of DPPH properties for raw ginseng, soft red ginseng, and ready-made red ginseng sap at different concentrations
표 Table 4. The 50% inhibition (EC₅₀) of DPPH on 1.0 ug/ml
표 Table 5. The degree of inhibition (%) of OH radical scavenging activity of raw ginseng, soft red ginseng, and ready-made red ginseng sap at different concentrations
표 Table 6. The 50% inhibition (EC₅₀) of OH on 1.0 ug/ml
표 Table 7. The degree of inhibition (%) of nitric oxide (NO) scavenging activity of raw ginseng, soft red ginseng, and ready-made red ginseng sap at different concentrations
표 Table 8. The 50% inhibition (EC₅₀) of NO on 1.0 ug/ml
그림 Fig. 1. Inorganic elements and texture analysis of soft red ginseng.
표 Table 9. Inorganic elements of several ginseng materials

AI 본문요약
AI-Helper

* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.

문제 정의

In this study, as soft red ginseng produced by new processing technology has been in soft condition for a considerable period of time, its use is expected to be expanded and varied. This study focused on investigating whether the antioxidant effects reduced or improved according to the new machining techniques.

대상 데이터

For the analysis of minerals and textures of soft red ginseng, raw, soft red, and red ginsengs were filmed and analyzed using FE-SEM (Field Emission Type Injection Electron Microscope) located in the Core Support Dynamic Center of Fusion Parts Materials in Dong-eui University. The magnification was 500 times, 1,000 times, and 2,000 times.

데이터처리

A variance analysis (ANOVA) was conducted for the effect on antioxidation by concentration of extracts, and the difference in average value by concentration was investigated for its significance in p<0.05, 0.01, or 0.001 by conducting Duncan's multi range test.
001 by conducting Duncan's multi range test. All experimental results were marked with average standard deviation, and statistical analysis was analyzed using the SPSS (v18.0, SPSS Inc., Chicago, IL, USA), the statistical program.

이론/모형

DPPH is a dark, purple and stable free radical and decreases in antioxidants and turns colorless. The DPPH scavenging activity was measured by the method by Blois [3]. 0.

성능/효과

This was not an accurate comparison because the red ginseng sap content of the products was not high only with about 10%, with 90% of other ingredients, which resulted in offset or partial interaction effects. Although it was impossible to compare the results with hard red ginseng because no results were reported so far, the antioxidant function was not impaired but increased even if ginseng was manufactured as soft red ginseng.
According to the reports from Han Bang Bio (China) commissioned by Ministry of Agriculture, it was analyzed that Korea Ginseng Products (white ginseng, red ginseng, X) and Chinese products (white ginseng, red ginseng, X) did not have higher calcium levels than other minerals [20]. The report showed that K (potassium) was the most (0.8 to 21 g/kg), followed by P (1.1 to 4.1 g/kg), and Ca (0.01 to 4.5 g/kg) (Table 9). We could see that soft red ginseng was much higher Ca.
As for antioxidant studies, the Superoxide dismutase (SOD) reported that Goryeo red ginseng significantly increased in activity [13]. This study found that antioxidant functions such as ABTS, DPPH, OH, and NO were significantly higher than raw ginseng by and large. Some anti-oxidant activities of soft red ginseng were also higher than products containing red ginseng sap.

참고문헌 (23)

Baeg, I. H. and So, S. H. 2013. The world ginseng market and the ginseng (Korea). J. Ginseng Res. 37, 1-7.

원문보기 상세보기
Baeg, J. H., Heo, J. Y., Fava, M., Mischoulon, D., Choi, K. W., Na, E. J., Cho, H. and Jeon, H. J. 2019. Effect of Korean red ginseng in individuals exposed to high stress levels: a 6-week, double-blind, randomized, placebo-controlled trial. J. Ginseng Res. 43, 402-407.

원문보기 상세보기
Blois, M. S. 1958. Antioxidant determinations by the use of a stable free radical. Nature 181, 1199-200.

상세보기
Brand-Williams, W., Cuvelier, M. E. and Berset, C. 1995. Use of free radical method to evaluate antioxidant activity. Food Sci. Technol. 28, 25-30.
Chang, J. K., Park, C. K. and Shim, K. H. 2003. Changes in chemical components of red ginseng processed from the fresh ginseng stored at low temperature. Kor. J. Food Preserv. 10, 158-161.
Cho, H. O., Lee, J. H., Cho, S. H. and Choi, Y. H. 1976. Approach to the extraction method on minerals of ginseng extract. Kor. J. Food Sci. Technol. 8, 95-106.
Chung, S. K., Osawa, T. and Kawakishi, S. 1997. Hydroxyl radical-scavenging effects of spices and scavengers from brown mustard (Brassica nigra). J. Biosci. Biotech. Biochem. 61, 118-123.

상세보기
Jung, K. H., Hong, H. D., Cho, C. W., Lee, M. Y., Choi, U. K. and Kim, Y. C. 2012. Phenolic acid composition and antioxidative activity of red ginseng prepared by high temperature and high pressure process. Kor. J. Food Nutr. 25, 827-832.

원문보기 상세보기
Kato, H., Lee, I. E., Chuyen, N. V., Kim, S. B. and Hayase, F. 1987. Inhibition of nitrosamine formation by nondialyzable melanoidins. Agr. Biol. Chem. 51, 1333-1338.
Keum, Y. S., Park, K. K., Lee, J. M., Chun, K. S., Park, J. H., Lee, S. K., Kwon, H. and Surh, Y. J. 1999. Antioxident and anti-tumor promoting activities of the methanol extract of heat processed ginseng. Cancer Lett. 150, 41-48.
Kim, D. Y. 1973. Studies on the browning of red ginseng. J. Kor. Agri. Chem. Soc. 16, 60-77.
Kim, E. O., Xu, J. L. and Um, B. H. 2016. Optimization of extraction of marker compounds from red ginsengs by accelerated solvent extraction using response surface methodology. J. Kor. Soc. Food Sci. Nutr. 45, 1162-1169.

원문보기 상세보기
Kim, J. Y., Kim, O. Y. and Lee, J. H. 2011. The effect of Korean panax red ginseng supplementation on antioxidant enzymes activities and lipid peroxides in Korean men. Kor. J. Lipidol. 21, 94-103.
Kim, S. E., Lee, Y. H., Park, J. H. and Lee, S. K. 1999. Ginsenoside-Rs3, a new diol-type ginseng saponin, selectively elevates protein levels of p53 and p21WAF1 leading to induction of apoptosis in SK-HEP-1 cells. Anticancer Res. 19, 487-491.

상세보기
Kim, W. Y., Kim, J. M., Han, S. B., Lee, S. K., Kim, N. D., Park, M. K., Kim, C. K. and Park, J. H. 2000. Steaming of ginseng at high temperature enhances biological activity. J. Nat. Prod. 63, 1702-1704.

상세보기
Kwon, H. J. and Park, C. S. 2008. Biological activity of extracts from Omija (Schizandra chinensis Baillon). Kor. J. Food Preserv. 15, 587-592.
Lee, M. J., Kim, E. H. and Rhee, D. K. 2008. Effects of Panax ginseng on stress. J. Ginseng Res. 32, 8-14.

원문보기 상세보기
Lee, S. T., Chu, K., Kim, J. M., Park, H. J. and Kim, M. 2007. Cognitive improvement by ginseng in Alzheimer's disease. J. Ginseng Res. 31, 51-53.

원문보기 상세보기
Lee, S. H., Kang, J. I., Lee, S. Y., Lee, S. H., Kang, J. I., Lee, S. Y., Lee, S. H., Kang, J. I. and Lee, S. Y. 2008. Saponin composition and physico-chemical properties of Korean red ginseng extract as affected by extracting conditions. J. Kor. Soc. Food Sci. Nutr. 37, 256-260.

원문보기 상세보기
Ministry of Agriculture, Food and Rural Affairs. 2016. Development of Technology for Distinguishing Country of Origin in Ginseng Products by Analysis of Inorganic and Organic Matters. Ministry of Agriculture, Food and Rural Affairs.
Nam, K. Y. 2005. The comparative understanding between red ginseng and white ginsengs, processed ginsengs (Panax ginseng C. A. Meyer). J. Ginseng Res. 29, 1-18.

원문보기 상세보기
Oliynyk, S. and Oh, S. 2013. Actoprotective effect of ginseng: improving mental and physical performance. J. Ginseng Res. 37, 144-166.

원문보기 상세보기
Zubia, M., Fabre, M. S., Kerjean, V. and Deslandes, E. 2009. Antioxidant and cytotoxic activities of some red algae (Rhodophyta) from Brittany coasts (France). Botanica Marina 52, 268-277.

상세보기

저자의 다른 논문 :

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증