[논문]대장암 진단용 단백질 바이오마커 측정을 위한 바이오센서 개발의 최신 연구 동향

리징징; 스윈페이; 이혜진

doi:10.14478/ace.2021.1040

대장암 진단용 단백질 바이오마커 측정을 위한 바이오센서 개발의 최신 연구 동향
Recent Research Trend of Biosensors for Colorectal Cancer Specific Protein Biomarkers 원문보기

공업화학 = Applied chemistry for engineering, v.32 no.3, 2021년, pp.253 - 259

리징징 (경북대학교 자연과학대학 화학과) , 스윈페이 (경북대학교 자연과학대학 화학과) , 이혜진 (경북대학교 자연과학대학 화학과)

Abstract ▼ AI-Helper

Colorectal cancer (CRC) is one of the most prevalent diseases in modern society, constituting a serious threat to global health. Currently, routine clinical screening and early removal of precancerous polyps are the most successful methods for reducing CRC incidence and mortality. However, the high cost and invasive detection of sigmoidoscopy and colonoscopy limited the CRC-screening participation and prevention. The emergence of biosensors provides an inexpensive, sensitive, less invasive tool for detecting CRC disease biomarkers. This review highlights some of recent efforts made on developing biosensors with electrochemical and optical techniques targeting CRC specific protein biomarkers for early diagnosis and prognosis, potential applications, and future perspectives.

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표/그림 (6)

그림 Figure 1. An overview of CRC-screening strategies highlighting different biosensing techniques for CRC protein biomarkers.
표 Table 1. Electrochemical Biosensors Developed for CRC Protein Biomarkers
그림 Figure 2. Schematic showing the (a) fabrication process of an origami paper based electrochemical biosensor and (b) modification of the working electrode for VEGF-C detection using SWCNTs, NMB, and AuNPs composites. Reproduced with permission from ref. [24] (Open access under the Creative Commons CC BY license, 2021 Springer Nature).
그림 Figure 3. Schematic showing the components of an LFIA strip for CEA detection. Reprinted with permission from ref. [41] (Open access under the Creative Commons CC-BY-NC-ND license, 2021 Wiley Periodicals).
표 Table 2. Some Examples of Optical Biosensors Developed for CRC Protein Biomarkers
그림 Figure 4. Schematic showing (a) the formation of the sandwich complex on an SPR gold chip for hnRNP A1 detection with an aptamer and anti-hnRNP A1 and (b) real-time analyses in CRC plasma samples. Reproduced with permission from ref. [6]. Copyright, 2020 Elsevier.

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저자의 다른 논문 :

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

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