다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
Journal of applied biological chemistry, v.64 no.3, 2021년, pp.299 - 307
신승미 (Anti-Aging Research Group, Gyeongnam Oriental Anti-Aging Institute) , 김지현 (Department of Food Science, Gyeongsang National University) , 조은주 (Department of Food Science and Nutrition, Pusan National University) , 김현영 (Department of Food Science, Gyeongsang National University)
AI-Helper
Accumulation of amyloid beta (Aβ) and oxidative stress are the most common reason of Alzheimer's disease (AD). In the present study, we investigated the cognitive improvement effects of butanol (BuOH) fraction from Momordica charantia in Aβ25-35-induced AD mouse model. To develop an AD...
Tiwari S, Atluri V, Kaushik A, Yndart A, Nair M (2019) Alzheimer's disease: pathogenesis, diagnostics, and therapeutics. Int J Nanomedicine 14: 5541-5554. doi: 10.2147/IJN.S200490
Scheltens P, Blennow K, Breteler MM, de Strooper B, Frisoni GB, Salloway S, Van der Flier WM (2016) Alzheimer's disease. Lancet 388: 505-517. doi: 10.1016/S0140-6736(15)01124-1
A Armstrong R (2019) Risk factors for Alzheimer's disease. Folia Neuropathol 57: 87-105. doi: 10.5114/fn.2019.85929
Chen GF, Xu TH, Yan Y, Zhou YR, Jiang Y, Melcher K, Xu HE (2017) Amyloid beta: structure, biology and structure-based therapeutic development. Acta Pharmacol Sin 38: 1205-1235. doi: 10.1038/aps.2017.28
Cheignon C, Tomas M, Bonnefont-Rousselot D, Faller P, Hureau C, Collin F (2018) Oxidative stress and the amyloid beta peptide in Alzheimer's disease. Redox Biol 14: 450-464. doi: 10.1016/j.redox.2017.10.014
Chen Z, Zhong C (2014) Oxidative stress in Alzheimer's disease. Neurosci Bull 30: 271-281. doi: 10.1007/s12264-013-1423-y
Kim GH, Kim JE, Rhie SJ, Yoon S (2015) The role of oxidative stress in neurodegenerative diseases. Exp Neurobiol 24: 325-340. doi: 10.5607/en.2015.24.4.325
Long JM, Holtzman DM (2019) Alzheimer Disease: An Update on Pathobiology and Treatment Strategies. Cell 179: 312-339. doi: 10.1016/j.cell.2019.09.001
Ishiura S, Yoshida T (2019) Plant-based vaccines for Alzheimer's disease. Proc Jpn Acad Ser B Phys Biol Sci 95: 290-294. doi: 10.2183/pjab.95.020
Gurbuz I, Akyuz C, Yesilada E, Sener B (2000) Anti-ulcerogenic effect of Momordica charantia L. fruits on various ulcer models in rats. J Ethnopharm 71: 77-82. doi: 0.1016/s0378-8741(99)00178-6
Oyedapo OO, Araba BG (2001) Stimulation of protein biosynthesis in rat hepatocytes by extracts of Momordica charantia. Phytother Res 15: 95-98. doi: 10.1002/ptr.682
Grover JK, Yadav SP (2004) Pharmacological actions and potential uses of Momordica charantia: a review. J. Ethnopharm 93: 123-132. doi: 10.1016/j.jep.2004.03.035
Jia S, Shen M, Zhang F, Xie J (2017) Recent advances in Momordica charantia: functional components and biological activities. Int J Mol Sci 18: 2555. doi: 10.3390/ijms18122555
Dandawate PR, Subramaniam D, Padhye SB, Anant S (2016) Bitter melon: a panacea for inflammation and cancer. Chin J Nat Med 14: 81-100. doi: 10.1016/S1875-5364(16)60002-X
Joshi A, Soni P, Malviya S, Kharia A (2017) Memory enhancing activity of Momordica charantia by scopolamine induced amnesia in rats. IJCAP 2: 11-18
Sin SM, Mok SY, Lee S, Cho KM, Cho EJ, Kim HY (2011) Protective effect of bitter melon (Momordica charantia) against oxidative stress. Cancer Prev Res 16: 86-92
Sin SM, Mok S-Y, Lee S, Cho KM, Cho EJ, Kim HY (2012) Antiinflammatory effect of bitter melon (Momordica charantia) in RAW 264.7 cell. Cancer Prev Res 17: 56-61
Laursen SE, Belknap JK (1986) Intracerebroventricular injections in mice. Some methodological refinements. J Pharmacol Methods 16: 355-357. doi: 10.1016/0160-5402(86)90038-0
Montgomery KC (1952) A test of two explanations of spontaneous alternation. J Comp Physiol Psychol 45: 287-293. doi: 10.1037/h0058118
Bevins RA, Besheer J (2006) Object recognition in rats and mice: a onetrial non-matching-to-sample learning task to study 'recognition memory'. Nat Protoc 1: 1306-1311. doi: 10.1038/nprot.2006.205
Morris R (1984) Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 11: 47-60. doi: 10.1016/0165-0270(84)90007-4
Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95: 351-358. doi: 10.1016/0003-2697(79)90738-3
Schmidt HH, Warner TD, Nakane M, Forstermann U, Murad F (1992) Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages. Mol Pharmacol 41: 615-624
Choi JR, Kim JH, Lee S, Cho EJ, Kim HY (2020) Protective effects of protocatechuic acid against cognitive impairment in an amyloid beta-induced Alzheimer's disease mouse model. Food Chem Toxicol 144: 111571. doi: 10.1016/j.fct.2020.111571
Butterfield DA, Boyd-Kimball D (2018) Oxidative stress, amyloid-β peptide, and altered key molecular pathways in the pathogenesis and progression of Alzheimer's disease. J Alzheimers Dis 62: 1345-1367. doi: 10.3233/JAD-170543.
Butterfield DA, Lauderback CM (2002) Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radic Biol Med 32: 1050-1060. doi: 10.1016/s0891-5849(02)00794-3
Islam MT (2017) Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders. Neurol Res 39: 73-82. doi: 10.1080/01616412.2016.1251711
Malik ZA, Singh M, Sharma PL (2011) Neuroprotective effect of Momordica charantia in global cerebral ischemia and reperfusion induced neuronal damage in diabetic mice. J Ethnopharmacol 133: 729-734. doi: 10.1016/j.jep.2010.10.061
Kim KB, Lee S, Kang I, Kim JH (2018) Momordica charantia ethanol extract attenuates H 2 O 2 -induced cell death by its antioxidant and antiapoptotic properties in human neuroblastoma SK-N-MC cells. Nutrients 10: 1368. doi: 10.3390/nu10101368
Nerurkar PV, Johns LM, Buesa LM, Kipyakwai G, Volper E, Sato R, Shah P, Feher D, Williams PG, Nerurkar VR (2011) Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation. J Neuroinflammation 8: 64. doi: 10.1186/1742-2094-8-64
Rosselli M, Keller PJ, Dubey RK (1998) Role of nitric oxide in the biology, physiology and pathophysiology of reproduction. Hum Reprod Update 4: 3-24. doi: 10.1093/humupd/4.1.3
Picon-Pages P, Garcia-Buendia J, Munoz FJ (2019) Functions and dysfunctions of nitric oxide in brain. Biochim Biophys Acta Mol Basis Dis 1865: 1949-1967. doi: 10.1016/j.bbadis.2018.11.007
Kim J-H, Choi JR, Cho EJ, Kim HY (2020) Protective effect of protocatechuic acid, phenolic compound of Momordica charantia, against oxidative stress and neuroinflammation in C6 glial cell. J Korean Med Obes Res 20: 10-19. doi: 10.15429/jkomor.2020.20.1
Gong J, Sun F, Li Y, Zhou X, Duan Z, Duan F, Zhao L, Chen H, Qi S, Shen J (2015) Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway. Neuro-pharmacology 91: 123-134. doi: 10.1016/j.neuropharm.2014.11.020
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.