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Biomedical science letters = 대한의생명과학회지, v.27 no.3, 2021년, pp.142 - 153
Choi, Jeong Won (Department of Herbology, College of Korean Medicine, Daegu Haany University) , Shin, Mi-Rae (Department of Herbology, College of Korean Medicine, Daegu Haany University) , Lee, Ji Hye (College of Korean Medicine, Semyung University) , Roh, Seong-Soo (Department of Herbology, College of Korean Medicine, Daegu Haany University)
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Liver fibrosis is a wound-healing response to chronic liver injury, which is caused by the continuous and excess deposition of extracellular matrix (ECM). The aim of this study is to investigate whether Uncaria rhynchophylla water extract (UR) can ameliorate thioacetamide (TAA)-induced liver fibrosi...
Araujo LCC, Feitosa KB, Murata GM, et al. Uncaria tomentosa improves insulin sensitivity and inflammation in experimental NAFLD. Sci Rep. 2018. 8: 11013.
Bataille AM, Manautou JE. Nrf2: a potential target for new therapeutics in liver disease. Clin Pharmacol Ther. 2012. 92: 340-348.
Bataller R, Brenner DA. Liver fibrosis. J Clin Invest. 2005. 115: 209-218.
Blois MS. Antioxidant determinations by the use of a stable free radical. Nature. 1958. 181: 1199-1200.
Brandes RP, Miller FJ, Beer S, et al. The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression. Free Radic Biol Med. 2002. 32: 1116-1122.
Carpino G, Morini S, Ginanni Corradini S, et al. Alpha-SMA expression in hepatic stellate cells and quantitative analysis of hepatic fibrosis in cirrhosis and in recurrent chronic hepatitis after liver transplantation. Dig Liver Dis. 2005. 37: 349-356.
da Silva BS, Paulino AMB, Taffarel M, et al. High sucrose diet attenuates oxidative stress, inflammation and liver injury in thioacetamide-induced liver cirrhosis. Life Sci. 2021. 267: 118944.
Friedman SL. Liver fibrosis - from bench to bedside. J Hepatol. 2003. 38 Suppl 1: S38-S53.
Gan D, Zhang W, Huang C, et al. Ursolic acid ameliorates CCl4-induced liver fibrosis through the NOXs/ROS pathway. J Cell Physiol. 2018. 233: 6799-6813.
Hajovsky H, Hu G, Koen Y, et al. Metabolism and toxicity of thioacetamide and thioacetamide S-oxide in rat hepatocytes. Chem Res Toxicol. 2012. 25: 1955-1963.
Han JT, Oh SJ, Kim HY, Park YD, Baek NI. Hyperin, Antioxidant compounds isolated from the branch of Uncaria rhynchophylla Miq. J Appl Biol Chem. 2000. 43: 78-80.
Han M, Liu X, Liu S, et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces hepatic stellate cell (HSC) activation and liver fibrosis in C57BL6 mouse via activating Akt and NF-κB signaling pathways. Toxicol Lett. 2017. 273: 10-19.
Han NK, Jung MG, Jeong YJ, et al. Plasma fibrinogen-like 1 as a potential biomarker for radiation-induced liver injury. Cells. 2019. 8: 1042.
Heitzman ME, Neto CC, Winiarz E, Vaisberg AJ, Hammond GB. Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae). Phytochemistry. 2005. 66: 5-29.
Islam T, Hasan MR, Roy A, et al. Screening of in-vitro antioxidant, brine shrimp lethality bioassay and antimicrobial activities of extracts of Bridelia retusa (L.) Spreng. fruit. Int J Pharm. 2015. 5: 1058-1067.
Jia R, Cao LP, Du JL, et al. Effects of carbon tetrachloride on oxidative stress, inflammatory response and hepatocyte apoptosis in common carp (Cyprinus carpio). Aquat Toxicol. 2014. 152: 11-19.
Kim HS, Lee YS, Oh SK, et al. Effect of ramulus et uncus uncariae on glucose oxidase-induced toxicity in cultured cerebral neurons. J Physiol & Pathol Korean Med. 2002. 16: 1016-1019.
Kim HY. Effects of water extracts of black tea on hepatic functional improvement and anti-fibrosis in rats. J East Asian Soc Diet Life. 2013. 23: 44-52.
Kim KH, Bae JH, Cha SW, Han SS, Park KH, Jeong TC. Role of metabolic activation by cytochrome P450 in thioacetamide-induced suppression of antibody response in male BALB/c mice. Toxicol Lett. 2000. 114: 223-235.
Kim ST, Kim JD, Lyu YS, Lee MY, Kang HW. Neuroprotective effect of some plant extracts in cultured CT105-induced PC12 cells. Biol Pharm Bull. 2006. 29: 2021-2024.
Koop AC, Thiele ND, Steins D, et al. Therapeutic targeting of myeloperoxidase attenuates NASH in mice. Hepatol Commun. 2020. 4: 1441-1458.
Lackner C, Tiniakos D. Fibrosis and alcohol-related liver disease. J Hepatol. 2019. 70: 209-304.
Lee UE, Friedman SL. Mechanisms of hepatic fibrogenesis. Best Pract Res Clin Gastroenterol. 2011. 25: 195-206.
Li J, Hu R, Xu S, et al. Xiaochaihutang attenuates liver fibrosis by activation of Nrf2 pathway in rats. Biomed Pharmacother. 2017. 96: 847-853.
Liang S, Kisseleva T, Brenner DA. The role of NADPH oxidases (NOXs) in liver fibrosis and the activation of myofibroblasts. Front Physiol. 2016. 7: 17.
Liu A, Shen Y, Du Y, et al. Esculin prevents lipopolysaccharide/D-Galactosamine-induced acute liver injury in mice. Microb Pathog. 2018. 125: 418-422.
Loh YC, Ch'ng YS, Tan CS, Ahmad M, Asmawi MZ, Yam MF. Mechanisms of action of Uncaria rhynchophylla ethanolic extract for its vasodilatory effects. J Med Food. 2017. 20: 895-911.
Marciniak S, Wnorowski A, Smolinska K, et al. Kynurenic acid protects against thioacetamide-induced liver injury in rats. Anal Cell Pathol (Amst). 2018: 2018. 1270483.
Ninan J, Feldman L. Ammonia levels and hepatic encephalopathy in patients with known chronic liver disease. J Hosp Med. 2017. 12: 659-661.
Piek A, Koonen DPY, Schouten EM, et al. Pharmacological myeloperoxidase (MPO) inhibition in an obese/hypertensive mouse model attenuates obesity and liver damage, but not cardiac remodeling. Sci Rep. 2019. 9: 18765.
Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biol Med. 1999. 26: 1231-1237.
Robinson SM, Mann DA. Role of nuclear factor kappaB in liver health and disease. Clin Sci (Lond). 2010. 118: 691-705.
Singleton VL, Rossi JA. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am J Enol Vitic. 1965. 16: 144-158.
Trefts E, Gannon M, Wasserman DH. The liver. Curr Biol. 2017. 27: R1147-R1151.
Wu CT, Deng JS, Huang WC, Shieh PC, Chung MI, Huang GJ. Salvianolic acid C against acetaminophen-induced acute liver injury by attenuating inflammation, oxidative stress, and apoptosis through inhibition of the Keap1/Nrf2/HO-1 Signaling. Oxid Med Cell Longev. 2019. 2019: 9056845.
Xu L, Yu Y, Sang R, Li J, Ge B, Zhang X. Protective effects of taraxasterol against ethanol-induced liver injury by regulating CYP2E1/Nrf2/HO-1 and NF-κB signaling pathways in mice. Oxid Med Cell Longev. 2018. 2018: 8284107.
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