$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Preclinical Alzheimer's disease and longitudinal driving decline 원문보기

Alzheimer's & dementia : Translational Research & Clinical Interventions, v.3 no.1, 2017년, pp.74 - 82  

Roe, Catherine M. (Department of Neurology, Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA) ,  Babulal, Ganesh M. (Department of Neurology, Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA) ,  Head, Denise M. (Department of Neurology, Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA) ,  Stout, Sarah H. (Department of Neurology, Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA) ,  Vernon, Elizabeth K. (Department of Neurology, Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA) ,  Ghoshal, Nupur (Department of Neurology, Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA) ,  Garland, Brad (My Tutor Learning Center, Belleville, IL, USA) ,  Barco, Peggy P. (Department of Occupational T) ,  Williams, Monique M. ,  Johnson, Ann ,  Fierberg, Rebecca ,  Fague, M. Scot ,  Xiong, Chengjie ,  Mormino, Elizabeth ,  Grant, Elizabeth A. ,  Holtzman, David M. ,  Benzinger, Tammie L.S. ,  Fagan, Anne M. ,  Ott, Brian R. ,  Carr, David B. ,  Morris, John C.

Abstract AI-Helper 아이콘AI-Helper

IntroductionLinks between preclinical Alzheimer's disease (AD) and driving difficulty onset would support the use of driving performance as an outcome in primary and secondary prevention trials among older adults (OAs). We examined whether AD biomarkers predicted the onset of driving difficulties am...

주제어

참고문헌 (44)

  1. 1 National Center for Statistics and Analysis Older population: 2014 data 2016 National Highway Traffic Safety Administration Washington, DC Report No.: DOT HS 812 273 

  2. 2 U.S. Census Bureau. Projections of the Population by Selected Age Groups and Sex for the United States: 2010 to 2050 [online]. Available at: http://www.census.gov/population/www/projections/summarytables.html . Accessed August 8, 2001. 

  3. 3 Duchek J.M. Carr D.B. Hunt L. Roe C.M. Xiong C. Shah K. Longitudinal driving performance in early stage dementia of the Alzheimer type J Am Geriatr Soc 51 2003 1342 1347 14511152 

  4. 4 Mayhew D.R. Simpson H.M. Ferguson S.A. Collisions involving senior drivers: high-risk conditions and locations Traffic Inj Prev 7 2006 117 124 16854705 

  5. 5 Insurance Institute for Highway Safety. Fatality facts 2013, Older people [online]. Available at: http://www.iihs.org/iihs/topics/t/older-drivers/fatalityfacts/older-people/2013 . Accessed December 23, 2016. 

  6. 6 Naumann R.B. Dellinger A.M. Zaloshnja E. Lawrence B.A. Miller T.R. Incidence and total lifetime costs of motor vehicle–related fatal and nonfatal injury by road user type, United States, 2005 Traffic Inj Prev 11 2010 353 360 20730682 

  7. 7 Gorrie C.A. Rodriguez M. Sachdev P. Duflou J. Waite P.M. Mild neuritic changes are increased in the brains of fatally injured older motor vehicle drivers Accid Anal Prev 39 2007 1114 1120 17920833 

  8. 8 Roe C.M. Barco P.P. Head D.M. Amyloid Imaging, cerebrospinal fluid biomarkers predict driving performance among cognitively normal individuals Alzheimer Dis Assoc Disord 2016 (in press) 

  9. 9 Vos S.J. Xiong C. Visser P.J. Jasielec M.S. Hassenstab J. Grant E.A. Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study Lancet Neurol 12 2013 957 965 24012374 

  10. 10 Klunk W.E. Engler H. Nordberg A. Wang Y. Blomqvist G. Holt D.P. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B Ann Neurol 55 2004 306 319 14991808 

  11. 11 Carrillo M.C. Blackwell A. Hampel H. Lindborg J. Sperling R. Schenk D. Early risk assessment for Alzheimer's disease Alzheimers Dement 5 2009 182 196 19328456 

  12. 12 Ott B.R. Jones R.N. Noto R.B. Amyloid deposition in preclinical Alzheimer's disease is associated with increased driving risk Alzheimers Dement (Amst) 2016 (In press) 

  13. 13 Friedrich M.J. Researchers test strategies to prevent Alzheimer disease JAMA 311 2014 1596 1598 24718971 

  14. 14 Bateman R.J. Xiong C. Benzinger T.L.S. Fagan A.M. Goate A. Fox N.C. Clinical and biomarker changes in dominantly inherited Alzheimer's disease N Engl J Med 367 2012 795 804 22784036 

  15. 15 Sperling R.A. Aisen P.S. Beckett L.A. Bennett D.A. Craft S. Fagan A.M. Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimers Dement 7 2011 280 292 21514248 

  16. 16 Snyder P.J. Kahle-Wrobleski K. Brannan S. Miller D.S. Schindler R.J. DeSanti S. Assessing cognition and function in Alzheimer's disease clinical trials: do we have the right tools? Alzheimers Dement 10 2014 853 860 25458309 

  17. 17 Ott B.R. Daiello L.A. How does dementia affect driving in older patients? Aging Health 6 2010 77 85 20368745 

  18. 18 Morris J.C. The Clinical Dementia Rating (CDR): current version and scoring rules Neurology 43 1993 2412 2414 

  19. 19 Carr D.B. Barco P.P. Wallendorf M.J. Snellgrove C.A. Ott B.R. Predicting road test performance in drivers with dementia J Am Geriatr Soc 59 2011 2112 2117 22092029 

  20. 20 Owsley C. Stalvey B. Wells J. Sloane M.E. Older drivers and cataract: driving habits and crash risk J Gerontol A Biol Sci Med Sci 54 1999 M203 M211 10219012 

  21. 21 Williams M.M. Roe C.M. Morris J.C. Stability of the Clinical Dementia Rating: 1979-2007 Arch Neurol 66 2009 773 777 19506139 

  22. 22 Folstein M.F. Folstein S.E. McHugh P.R. Mini-mental State: a practical method for grading the cognitive state of patients for the clinicians J Psychiatr Res 12 1975 189 198 1202204 

  23. 23 Weintraub S. Salmon D. Mercaldo N. Ferris S. Graff-Radford N.R. Chui H. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery Alzheimer Dis Assoc Disord 23 2009 91 101 19474567 

  24. 24 Klunk W.E. Amyloid imaging as a biomarker for cerebral β-amyloidosis and risk prediction for Alzheimer dementia Neurobiol Aging 32 2011 S20 S36 22078170 

  25. 25 Mintun M.A. LaRossa G.N. Sheline Y.I. Dence C.S. Lee S.Y. Mach R.H. [11 C] PIB in a nondemented population: potential antecedent marker of Alzheimer disease Neurology 67 2006 446 452 16894106 

  26. 26 Fischl B. Salat D.H. Busa E. Dieterich M. Haselgrove C. van der Kouwe A. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain Neuron 33 2002 341 355 11832223 

  27. 27 Fagan A.M. Mintun M.A. Mach R.H. Lee S.Y. Dence C.S. Shah A.R. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Aá42 in humans Ann Neurol 59 2006 512 519 16372280 

  28. 28 Cruchaga C. Kauwe J.S. Nowotny P. Bales K. Pickering E.H. Mayo K. Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease Hum Mol Genet 21 2012 4558 4571 22821396 

  29. 29 Harris P.A. Taylor R. Thielke R. Payne J. Gonzalez N. Conde J.G. Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support J Biomed Inform 42 2009 377 381 18929686 

  30. 30 Blennow K. Dubois B. Fagan A.M. Lewczuk P. De Leon M.J. Hampel H. Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease Alzheimers Dement 11 2015 58 69 24795085 

  31. 31 Snider B.J. Fagan A.M. Roe C.M. Shah A.R. Grant E.A. Xiong C. Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer type Arch Neurol 66 2009 638 645 19433664 

  32. 32 Kaplan E.L. Meier P. Nonparametric estimation from incomplete observations J Am Stat Assoc 53 1958 457 481 

  33. 33 Cox D.R. Regression models and life-tables Breakthroughs in statistics 1992 Springer New York 527 541 

  34. 34 Verbeke G. Molenberghs G. Linear mixed models for longitudinal data 2009 Springer Science & Business Media New York 

  35. 35 Obermann K.R. Morris J.C. Roe C.M. Exploration of 100 commonly used drugs and supplements on cognition in older adults Alzheimers Dement 9 2013 724 732 23954027 

  36. 36 Benjamini Y. Hochberg Y. Controlling the false discovery rate—a practical and powerful approach to multiple J R Stat Soc Ser B Method 57 1995 289 300 

  37. 37 Hird M.A. Egeto P. Fischer C.E. Naglie G. Schweizer T.A. Pachana N. A systematic review and meta-analysis of on-road simulator and cognitive driving assessment in Alzheimer's disease and mild cognitive impairment J Alzheimers Dis 53 2016 713 729 27176076 

  38. 38 Casutt G. Martin M. Keller M. Jäncke L. The relation between performance in on-road driving, cognitive screening and driving simulator in older healthy drivers Transportation Res F Traffic Psychol Behav 22 2014 232 244 

  39. 39 Kozauer N. Katz R. Regulatory innovation and drug development for early-stage Alzheimer's disease N Engl J Med 368 2013 1169 1171 23484795 

  40. 40 Silverberg N.B. Ryan L.M. Carrillo M.C. Sperling R. Petersen R.C. Posner H.B. Assessment of cognition in early dementia Alzheimers Dement 7 2011 e60 e76 23559893 

  41. 41 Ott B.R. Davis J.D. Bixby K. Video feedback intervention to enhance the safety of cognitively impaired older adults Am J Occup Ther 2016 (In press) 

  42. 42 Babulal G. Addison A. Ghoshal N. Stout S.H. Vernon E.K. Sellan M. Development and interval testing of a naturalistic driving methodology to evaluate driving behavior in clinical research [version 2; referees: 2 approved] F1000Res 5 2016 1716 27785360 

  43. 43 Aksan N. Dawson J.D. Emerson J.L. Yu L. Uc E.Y. Anderson S.W. Naturalistic distraction and driving safety in older drivers Hum Factors 55 2013 841 853 23964422 

  44. 44 Babulal G. Traub C. Webb M. Stout S.H. Addison A. Carr D.B. Creating a driving profile for older adults using GPS devices and naturalistic driving methodology [version 1; referees: 1 approved, 1 approved with reservations] F1000Res 5 2016 2376 27990264 

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

이 논문과 함께 이용한 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로