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NTIS 바로가기소아청소년정신의학 = Journal of the Korean Academy of Child and Adolescent Psychiatry, v.21 no.3, 2010년, pp.133 - 140
정용우 (미국 예일대학교 의과대학 면역학교실) , 박태원 (전북대학교 의학전문대학원 정신과학교실)
Tic disorders, including Tourette syndrome, are known as neurobiologic disorders and as such, much emphasis has been placed on isolating genetic determinants. Although previous reports involving studies of discordance among monozygotic twins have shown the importance of genetic predisposition, they ...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
뚜렛증후군을 포함한 틱장애는 어떠한 질환을 동반하는가? | 1%가 뚜렛증후군에 이환 된다고 보고했다.1) 뚜렛증후군을 포함한 틱장애는 주의력결핍 과잉행동장애(attention-deficit hyperactivity disorder, ADHD), 강박장애를 비롯해 다양한 신경정신의학적 질환을 동반하면서 만성적으로 완화와 악화를 반복하는데, 이환된 소아청소년의 학습 및 교우관계에 영향을 주며 일부는 성인기까지 증상이 이어져 직업 및 대인관계에 심각한 지장을 초래한다. | |
틱장애란 무엇인가? | 틱장애(tic disorder)는 주로 소아청소년 시기에 발병하며 반복적이고 불수의적인 이상 근육운동을 보이거나 소리를 내는 장애로서, 유병률은 전체 소아의 1~13%에 이른다. 1년 이상 틱증상이 지속되는 만성 틱장애 중에서도 가장 심한 증상을 보이는 임상 아형으로 알려진 뚜렛증후군(Tourette’s syndrome)은 과거에는 비교적 드물다고 알려졌으나, 최근 연구에서는 전체 소아의 0. | |
틱장애의 증상을 발병과 악화시키는 관련 요인은 무엇이 있는가? | 유전적 요인, 스트레스를 비롯한 생활사건, 감염을 비롯한 신체적 질환 등 다양한 요인이 틱증상의 발병과 악화에 관여하는 것으로 알려져 있으나, 현재까지의 연구는 주로 유전 요인을 비롯한 신경생물학적 요인에 집중되어 있다. 그러나 모든 발병이 유전적으로 설명되지는 않으며 다른 신경정신의학적 질환처럼 유전적 요인과 환경적 요인의 상호작용이 발병이나 악화에 관여할 것으로 예상된다. |
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