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NTIS 바로가기대한예방한의학회지 = Journal of Society of Preventive Korean Medicine, v.15 no.2, 2011년, pp.51 - 67
이영준 (대구한의대학교 한의과대학 예방의학교실) , 한창현 (한국한의학연구원 전통의학정보연구본부) , 전원경 (한국한의학연구원 한의융합연구본부) , 백경민 (대구한의대학교 한의과대학 심계내과) , 전우현 (대구한의대학교 한의과대학 신경과) , 최성훈 (대구한의대학교 한의과대학 해부학교실)
The average human life span has increased due to the development of modern medicine and science, resulting in prolonged life expectancy and increase in the population counts of the geriatric age group. In particular, a dramatic increase of elderly patients suffering from senile disorders including n...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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Memantine이란 무엇인가? | Memantine은 N-methyl-D-aspartate(NMDA) glutamate receptor를 차단해서 glutamatergic system을 활성화시킴으로써 알츠하이머병을 치료하는 약물이다. Memantine의 투여방법은 하루 10mg, 28주간 투여하였다. | |
Galantamine의 개발 목적은 무엇인가? | Galantamine은 acetylcholinesterase(AChE)를 억제함으로써 경도에서 중등도의 알츠하이머병과 혈관성으로 기인하는 인지장애를 치료할 목적으로 개발되었다. Galantamine의 투여용량은 8~24mg/day까지 투여했으며 평균 6개월간 투여하였다. | |
한의학에서 치매의 발생 원인은 무엇으로 정리되는가? | 한의학에서 치매는 健忘, 呆病, 癲狂, 虛勞 등의 범주로 분류하고 있으며, 張景岳이 『景岳全書․雜證謨』에서 痴獃證이라 하여 오늘날 치매와 유사한 증상을 처음 언급하였다.70) 치매 발생의 원인으로는 음식과 攝生의 부적절로 인한 濕痰阻竅, 情志의 抑鬱이나 정신적 shock 또는 타박손상으로 인한 氣滯血瘀, 大病後와 衰弱으로 인한 肝腎陰虛, 先天不足의 虛弱이나 유전적 결함으로 인한 髓海不足 등으로 정리하고 있다.71, 72) 본 연구에서도 살펴 본 문헌들에서도 혈관성치매에 대한 변증을 髓海不足, 肝腎虧虛, 脾腎兩虛, 心肝火盛, 痰濁阻竅, 氣滯血瘀로 하여 변증에 맞는 약물을 조합하여 유효성을 평가하고 있었다. |
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