최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기공업화학 = Applied chemistry for engineering, v.32 no.1, 2021년, pp.1 - 9
민창호 (경북대학교 공과대학 응용화학공학부 응용화학과) , 하헌수 (경북대학교 공과대학 응용화학공학부 응용화학과) , 전종호 (경북대학교 공과대학 응용화학공학부 응용화학과)
Alzheimer's disease (AD), an irreversible degenerative disorder, is associated with accumulation and aggregation of amyloid-β peptides, hyperphosphorylated tau proteins, and high level of metal ions in the brain. Up to date, there is no effective therapeutic agent to stop the progress of the di...
* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.
J. Greenwald and R. Riek, Biology of amyloid: Structure, function, and regulation, Structure, 18, 1244-1260 (2018).
P. Faller, C. Hureau, and O. Berthoumieu, Role of metal ions in the self-assembly of the Alzheimer's amyloid-beta peptide, Inorg. Chem., 52, 12193-12206 (2013).
Y.-H. Suh and F. Checler, Amyloid precursor protein, presenilins, and α-synuclein: Molecular pathogenesis and pharmacological applications in Alzheimer's disease, Pharmacol. Res., 54, 469-525 (2002).
U. C. Mu?ller, T. Deller, and M. Korte, Not just amyloid: Phy- siological functions of the amyloid precursor protein family, Nat. Rev. Neurosci., 18, 281-298 (2017).
K. P. Kepp, Bioinorganic chemistry of Alzheimer's disease, Chem. Rev., 112, 5193-5239 (2012).
K. Iqbal, A. del C. Alonso, S. Chen, M. O. Chohan, E. El-Akkad, C.-X. Gong, S. Khatoon, B. Li, F. Liu, A. Rahman, H. Tanimukai, and I. Grundke-Iqbal, Tau pathology in Alzheimer disease and other tauopathies, Biochim. Biophys. Acta, Mol. Basis Dis., 1739, 198-210 (2005).
K. V. Kuchibhotla, S. Wegmann, K. J. Kopeikina, J. Hawkes, N. Rudinskiy, M. L. Andermann, T. L. Spires-Jones, B. J. Bacskai, and B. T. Hyman, Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo, Proc. Natl. Acad. Sci. U. S. A., 111, 510-514 (2014).
G. Lippens, A. Sillen, I. Landrieu, L. Amniai, N. Sibille, P. Barbier, A. Leroy, X. Hanoulle, and J.-M. Wieruszeski, Tau aggregation in Alzheimer's disease, Prion, 1, 21-25 (2007).
I. Grundke-Iqbal, K. Iqbal, Y. C. Tung, M. Quinlan, H. M. Wisniewski, and L. I. Binder, Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology, Proc. Natl. Acad. Sci. U. S. A., 83, 4913-4917 (1986).
A. Lorenzo and B. A. Yankner, Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red, Proc. Natl. Acad. Sci. U. S. A., 91, 12243-12247 (1994).
W. E. Klunk, M. L. Debnath, and J. W. Pettegrew, Chrysamine-G binding to Alzheimer and control brain: Autopsy study of a new amyloid probe, Neurobiol. Aging, 16, 541-548 (1995).
H. Naiki, K. Higuchi, M. Hosokawa, and T. Takeda, Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavine T, Anal. Biochem., 177, 244-249 (1989).
W. E. Klunk, B. J. Bacskai, C. A. Mathis, S. T. Kajdasz, M. E. McLellan, M. P. Frosch, M. L. Debnath, D. P. Holt, Y. Wang, and B. T. Hyman, Imaging Aβ plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered congo red derivative, J. Neuropathol. Exp. Neurol., 61, 797-805 (2002).
M. Hintersteiner, A. Enz, P. Frey, A.-L. Jaton, W. Kinzy, R. Kneuer, U. Neumann, M. Rudin, M. Staufenbiel, M. Stoeckli, K.-H. Wiederhold, and H.-U. Gremlich, In vivo detection of amyloid-β deposits by near-infrared imaging using an oxazine-derivative probe, Nat. Biotechnol., 23, 577-583 (2005).
A. G. Vlassenko, T. L. S. Benzinger, and J. C. Morris, PET amyloid-beta imaging in preclinical Alzheimer's disease, Biochim. Biophys. Acta, Mol. Basis Dis., 1822, 370-379 (2012).
C. A. Mathis, N. S. Mason, B. J. Lopresti, and W. E. Klunk, Development of positron emission tomography β-amyloid plaque imaging agents, Semin. Nucl. Med., 42, 423-432 (2012).
P. Verwilst, H. S. Kim, S. Kim, C. Kang, and J. S. Kim, Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores, Chem. Soc. Rev., 47, 2249-2265 (2018).
P. Verwilst, H.-R. Kim, J. Seo J, N.-W. Sohn, S.-Y. Cha, Y. Kim, S. Maeng, J.-W. Shin, J. H. Kwak C. Kang, and J. S. Kim, Rational design of in vivo tau tangle-selective near-infrared fluorophores: expanding the bodipy universe, J. Am. Chem. Soc., 139, 13393-13403 (2017).
E. E. Nesterov, J. Skoch, B. T. Hyman, W. E. Klunk, B. J. Bacskai and T. M. Swager, In vivo optical imaging of amyloid aggregates in brain: Design of fluorescent markers, Angew. Chem. Int. Ed., 44, 5452-5456 (2008).
S. B. Raymond, J. Skoch, I. D. Hills, E. E. Nesterov, T. M. Swager, and B. J. Bacskai, Smart optical probes for near-infrared fluorescence imaging of Alzheimer's disease pathology, Eur. J. Nucl. Med. Mol. Imaging, 35, 93-98 (2008).
Y. Wang, T. Liu, E. Zhang, S. Luo, X. Tan, and C. Shi, Preferential accumulation of the near infrared heptamethine dye IR-780 in the mitochondria of drug-resistant lung cancer cells, Biomaterials, 35, 4116-4124 (2014).
G. Lv, A. Sun, P. Wei, N. Zhang, H. Lan, and T. Yi, A spiropyran-based fluorescent probe for the specific detection of b-amyloid peptide oligomersin Alzheimer's disease, Chem. Commun., 52, 8865 (2016).
J. W. Yan, J. Y. Zhu, K. X. Zhou, J. S. Wang, H. Y. Tan, Z. Y. Xu, S. B. Chen, Y. T. Lu, M. C. Cui, and L. Zhang, Neutral merocyanine dyes: for in vivo NIR fluorescence imaging of amyloid-β plaques, Chem. Commun., 53, 9910-9913 (2017).
H. L. Yang, S. Q. Fang, Y. W. Tang, C. Wang, H. Luo, L. L. Qu, J. H. Zhao, C. J. Shi, F. C. Yin, X. B. Wang, and L. Y. Kong, A hemicyanine derivative for near-infrared imaging of betaamyloid plaques in Alzheimer's disease, Eur. J. Med. Chem., 179, 736-743 (2019).
H. Y. Kim, U. Sengupta, P. Shao, M. J. Guerrero-Munoz, R. Kayed, and M. Bai, Alzheimer's disease imaging with a novel Tau targeted near infrared ratiometric probe, Am. J. Nucl. Med. Mol. Imaging, 3, 102-117 (2013).
S. Aggarwal, H. Ichikawa, Y. Takada, S. K. Sandur, S. Shishodia, and B. B. Aggarwal, Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IκBα kinase and Akt activation, Mol. Pharmacol., 69, 195-206 (2006).
C. Ran, X. Xu, S. B. Raymond, B. J. Ferrara, K. Neal, B. J. Bacskai, Z. Medarova, and A. Moore, Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits, J. Am. Chem. Soc., 131, 15257-15261 (2009).
X. Zhang, Y. Tian, Z. Li, X. Tian, H. Sun, H. Liu, A. Moore, and C. Ran, Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's disease, J. Am. Chem. Soc., 135, 16397-16409 (2013).
X. Zhang, Y. Tian, C. Zhang, X. Tian, A. W. Ross, R. D. Moir, H. Sun, R. E. Tanzi, A. Moore, and C. Ran, Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease, Proc. Natl. Acad. Sci. U. S. A., 112, 9734-9739 (2015).
Y. Li, J. Yang, H. Liu, J. Yang, L. Du, H. Feng, Y. Tian, J. Cao, and C. Ran, Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species, Chem. Sci., 8, 7710-7717 (2017).
K. S. Park, Y. Seo, M. K. Kim, K. Kim, Y. K. Kim, H. Choo, and Y. A. Chong, Curcumin-based molecular probe for near-infrared fluorescence imaging of tau fibrils in Alzheimer's disease, Org. Biomol. Chem., 13, 11194-11199 (2015).
Y. Seo, K. S. Park, T. Ha, M. K. Kim, Y. J. Hwang, J. Lee, H. Ryu, H. Choo, and Y. Chong, A smart near-infrared fluorescence probe for selective detection of tau fibrils in Alzheimer's disease, ACS Chem. Neurosci., 7, 1474-1481 (2016).
K. S. Park, K. Yoo, M. K. Kim, W. Jung, Y. K. Choi, and Y. Chong, A novel probe with a chlorinated α cyanoacetophenone acceptor moiety shows near-infrared fluorescence specific for tau fibrils, Chem. Pharm. Bull., 65, 1113-1116 (2017).
K.-S. Park, M. K. Kim, Y. Seo, T. Ha, K. Yoo, S. J. Hyeon, Y. J. Hwang, J. Lee, H. Ryu, H. Choo, and Y. A. Chong, Difluoroboron β-diketonate probe shows "Turn-on" near-infrared fluorescence specific for tau fibrils, ACS Chem. Neurosci., 8, 2124-2131 (2017).
A. Loudet and K. Burgess, BODIPY dyes and their derivatives: Syntheses and spectroscopic properties, Chem. Rev., 107, 4891-4932 (2007).
H. Watanabe, M. Ono, K. Matsumura, M. Yoshimura, H. Kimura, and H. Saji, Molecular imaging of ß-amyloid plaques with near-infrared boron dipyrromethane (BODIPY)-based fluorescent probes, Mol. Imaging, 12, 338-347 (2013).
L. Teoh, D. Su, S. Sahu, S. W. Yun, E. Drummond, F. Prelli, S. Lim, S. Cho, S. Ham, T. Wisniewski, and Y. T. Chang, A chemical fluorescent probes for the detection of Aβ oligomers, J. Am. Chem. Soc., 137, 13503 (2015).
W. Ren, J. Zhang, C. Peng, H. Xiang, J. Chen, C. Peng, W. Zhu, R. Huang, H. Zhang, and Y. Hu, Fluorescent imaging of beta-amyloid using BODIPY based near-infrared off-on fluorescent probe, Bioconjugate Chem., 29, 3459-3466 (2018).
P. Verwilst, H.-R. Kim, J. Seo, N.-W. Sohn, S.-Y. Cha, Y. Kim, S. Maeng, J.-W. Shin, J. H. Kwak, C. Kang, and J. S. Kim, Rational design of in vivo tau tangle-selective near infrared fluorophores: Expanding the BODIPY universe, J. Am. Chem. Soc., 139, 13393-13403 (2017).
W. Yang, Y. Wong, O. T. Ng, L. P. Bai, D. W. Kwong, Y. Ke, Z. H. Jiang, H. W. Li, K. K. Yung, and M. S. Wong, Inhibition of beta-amyloid peptide aggregation by multifunctionalcarbazole-based fluorophores, Angew. Chem. Int. Ed., 51, 1804-1810 (2012).
Y. Li, D. Xu, S. L. Ho, H. W. Li, R. Yang, and M. S. Wong, A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation, Biomaterials, 94, 84-92 (2016).
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문
※ AI-Helper는 부적절한 답변을 할 수 있습니다.