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In Vitro Repression of Brca1-associated RING Domain Gene, Bard1 , Induces Phenotypic Changes in Mammary Epithelial Cells

The Journal of cell biology, v.143 no.5, 1998년, pp.1329 - 1339  

Irminger-Finger, Irmgard (Laboratory of Biology of Aging and Department of Geriatrics, University of Geneva) ,  Soriano, Jesus V. (and Division of Oncology and Department of Morphology, University of Geneva Medical Center, CH-1226 Geneva, Switzerland) ,  Vaudan, Geneviève (Laboratory of Biology of Aging and Department of Geriatrics, University of Geneva) ,  Montesano, Roberto (and Division of Oncology and Department of Morphology, University of Geneva Medical Center, CH-1226 Geneva, Switzerland) ,  Sappino, André-Pascal (Laboratory of Biology of Aging and Department of Geriatrics, University of Geneva)

Abstract AI-Helper 아이콘AI-Helper

BRCA1-associated RING domain (BARD1) was identified as a protein interacting with the breast cancer gene product BRCA1. The identification of tumorigenic missense mutations within BRCA1 that impair the formation of BARD1–BRCA1 complexes, and of BARD1 mutations in breast carcinomas, sustain th...

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참고문헌 (37)

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